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Beta-lactam ring Portion of penicillin chemical structure responsible for antibacterial activity.
Beta lactamase General term use for any of several enzymes that split the 4 atom beta lactum ring structure
Penicillinase A beta-lactamase that splits the ring in penicillin antibiotics
Penicillin-binding proteins(PBPs) Enzymes used by bacteria to build bacterial cell walls that are targes for penicillins and r/t antibiotics.
peptidoglycan A wall network of carbohydrates and protein chains.
Acquired resistance When a microbe is no longer affected by a drug following treatment with anti-infectives.
Aerobic Oxygen environment
Anaerobic Without oxygen environment
Antibiotic Substance produced by a microorganism that inhibits or kills other microorganisms.
Anti-infective General term for any medication that is effective against pathogens.
Bacteriocidal Substance that kills bacteria
Bacteriostatic Inhibits growth of bacteria.
Broad-spectrum antibiotic Effective against a wide range of microorganisms
Conjugation Direct transfer of small pieces of DNA from one bacterium to another.
Culture and sensitivity testing (C&S) Exposing the microbe to antibiotics to determine which antibiotic is effective.
Endotoxins Harmful non-proteins that are part of the normal cell wall of gram-negative bacteria
Gram negative Don’t stain purple because they have an outer envelope.
Gram positive Bacteria that stain purple because they have no outer envelope
Host flora Microorganisms that normally inhabit the body.
Invasiveness Is the ability of a pathogen to grow extremely rapidly and cause direct damage to surrounding tissues by their sheer numbers
Microbial antagonism Conditions of various host flora in competition with each other for physical space and nutrients that helps protect the host from being overrun by pathogenic organisms
Mutations Bacteria makes errors in duplicating genetic codes.
Narrow-spectrum antibiotic An anti-infective that is effective against only one or a small number of organisms.
Nosocomial infections Infections inquired in a hospital.
Pathogenicity Ability of an organism to cause disease in humans
Pathogens Organisms capable of causing disease
Superinfections New infection caused by an organism different from the one causing the initial infection; usually an adverse effect of anti-infective therapy.
Virulence Severity of disease that a pathogen is able to cause.
Created by: polosport