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Stack #842920

Thiazide diuretic: Block Na reduction in cortical portion of ascending tubule;water excreted w/ Na --> decreased blood volume - AZIDE Chlorothazide (Diuril), Hydrochlorothiazide (Hydrodiuril), Indapamide (Lozol), Metolazone (Zaroxlyn)
Loop Diuretic: Block Na and water reabsorption in medullary portion of ascending tubule; decreased blood volume - AMIDE Butmetanide (Bumex), Furosemide (Lasix), Torsemide (Demadex)
Potassium Sparing Diuretic: Inhibit aldosterone: Na excreted in exchange for K; avoid salt substitutes because they are often potassium based Spironolactone (Aldactone), Triamterene (Dyrenium)
Adrenergic Inhibitors Beta blockers: Block beta adrenergic receptors in SNS; decr heart rate and BP; Decr renin release by kidneys - OLOL Atenolol (Tenormin), Metoprolol (lopressor), Nadolol (Corgard), Propanolol ( Inderal)
Centrally Acting alpha blockers: Decreases PVR Clonidine (catapres), Methyldopa (Aldomet)
Alpha-1 adrenergic blockers: Decreased PVR Prazosin (Minipress), Terazosin (Hytrin)
Combined alpha and beta blockers: Same as beta blockers, Block beta-adrenergic receptors in SNS; decr heart rate and BP; Decr renin release by kidney Labetolol (normodyne, trandate)
Vasodilators: Dilate perpheral vessels by directly relaxing vascular smooth muscle Hydralazine (Apresoline), Minoxdil (Loniten)
ACE inhibitors: Inhibit conversion of angiotensin - PRIL Captopril (Capoten), Enalapril (Vasotec), Lisinopril (Prinvil), Benzapril (Lotensin), Fosinopril (Monopril), Quinopril (Accupril)
Angiotensin II Receptor blockers: Blocks effect of angiotensin II at the receptor - TAN Losartan (Cozaar), Irbesartan (Avapro), Valsartan (Diovan)
Calcium Channel Blockers: Inhibit influx of Ca into muscle cells; promote vasodilation and decr PVR by relaxing vascular smooth muscle Diltiazen (Cardizen), Nifedipine Procardia, Verapamil ( Calan, isoptin), Verapamil SR, Amlodipinr (Norvasc
Lispro (Humalog), glulisine (Apidra), aspart (Novolog) Rrr Rrr Rapid
Humulin and Novolin R shoRt
Humulin N and Novolin N Intermediate
Humulin U Lonngg acting
Onset 10-12mins, Peak 1-2hrs, duration 2-4hrs Rapid
Onset 30mins-1hr, Peak 2-3hr, Duration 4-6hr shoRt
Onset 2-4hr, Peak 4-12hr, 16-20hrs Intermediate
Onset 6-8hr, Peak 12-14hr, 20-30hr Long Acting
Minimal side effects Angiotensin II Receptor Blockers
dizziness Calcium channel blockers
incr BUN, Uric acid, blood glucose, HypoK, postural hypotension, fatigue Thiazide Diuretics
hypoK, postural hypotension, incr uric acid loop diuretics
Potassium-Sparing Diuretics hyperK
adrenergic inhibitors beta blockers Bradycardia, fatigue, mental depression, contraindicated with asthma, COPD, and heart block, DM may not have usual hypoglycemic symptoms
Centrally acting alpha blockers drowsiness, sedation, orthostatic hypotension
Alpha-1 adrenergic blockers first dose syncope, ortho hypotension
combined alpha and beta blockers ortho hypotension, bronchospasm
vasoldilators HA, dizziness
ACE inhibitors First dose hypotension, cough, Hyper K, renal function, BUN, creatinine
Created by: angelinajayde