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Nur100-Concept/Pharm

pharmacology

QuestionAnswer
Acute Care on the spot right now; more critical
maintenance COPD, obstruct treatment of chronic disease.
Supplemental taking insulin B12 shot
Palliative end of life, hospice, not a place but a way of care
Supportive things that have to be repaire
Prophylactic giving someone antibiotics or immunity vaccine guarding from or preventing the spread or occurrence of disease or infection tending to prevent or ward off : preventive
what are the goals of meds in management ? restore health, return to healthy baseline
What are some therapies? acute care, maintenance, supplement, palliative, suppotive, prophylacitc
What are some Roles of the RN in a Pharmacological Intervention? 1.Preparation (giving Iv meds) 2.Assessment- see if person needs meds 3.administration-right amount and time and dose 4.teaching/education:patient compliance (better they understand better they will comply) 5. Evaluation/outcome
Pure Food and Drug Act of 1906? successful model for re-legalization of currently prohibited drugs by requiring accurate labels, monitoring of purity and dose, and consumer education.(cocaine, heroin now needs labeling)
Federal Food and Drug Act of 1938? Federal Food and Drug Act of 1938 Does not use HOmiopathic remedies; all drugs minus home-remedies need to be approved
Comprehensive Drug Abuse Prevention and Control Act of 1970 ? "schdule 1" scheduling controlled drugs-govt funded addiction programs
Drug Regulation Reform Act of 1978 ? Drug Regulation Reform Act of 1978 -trying to get the thing(drug)on the market quicker rather than later
what legal act happened in 1987? Food and Drug Administration and Modernization Act of 1987
define "chemical" name? describes the med in terms of its chemical make-up
Define "generic" name? name is given from Gov't (so its easy to remember)
Define "Brand and trade" name? assigned by the manufactured; name used to market drug to the public, approved by FDA
What is the chemical, Generic, and brand name for Tylenol? chem: n-acetyl-para-aminophenol generic:Acetaminophine brand:tylenol
What are the Drug Routes tha pertain in Enteral/Oral? goes straight to intestine/GI tract: 1.PO (by mouth) 2.SL (under the tongue) 3.Buccal (cheek)
What are the Drug routes pertaining to Perental? -Irriversable 1.Intravenous-instant absorption 2.Subcutaneous-water soluable meds absorb into circulation quicker (I.M.internal Medication) 3.Intramuscular-water soluablemeds absorb into circulation quicker 4.Topical,Inhaled, Intrathecal,Epidural etc.
Intrathecal/Epidural? injection in spinal canal/injection of drugs through a catheter placed into the epidural space. The injection can cause both a loss of sensation (anaesthesia) and a loss of pain (analgesia),
Which medication absorbs better? I.M. or Subcutaneous? I.M.
Pharmacokinetics WHAT BODY DOES TO DRUG Absorption:drug moving from admin site into the blood. Distribution-drug moving thru body tissues to its destination metabolism-biotranformation,change of chem structure by enzymes excretiondrug moving out of the body kidney urinate
PharmacoDynamics WHAT DRUG DOES TO THE BODY.. 1.receptor action-lock and key affinity,agonist,antagonist 2.enzyme action-enhanced or inhibit enzyme 3.nonselective action-drug lands and sits there on cell surface changing cell structure
The unbound portion is considered? "free" and active.
When albumin connects to a drug is it inactive or active?does the drug levels go up? inactive increasing the drug levels.
What happens when there is low albumin level? toxicity goes up ex: anorexia, burns, elderly.
which organ is most responsible for metabolism of drugs? Liver
Hepatic metablism involves the activity of a very large class of enzymes known as ________? Cytochrome P-450 enzyme.
what do Cytochrome P-450 control ? enzyme controls a variety of reactions that aid in the metabolism of medications.
Onset response elicited, M.E.C. (minimum effective concentration)
Peak med is at its highest concentration
Trough med is at its lowest concentration
Duration the time the med is at a level that can elicit a response
Plateau thru repeated doses we maintain therapeautic effect
half-life time it takes 50% of the med to be excreted from the body
therapeutic range amt of med that must be present in serum to continue the desired resonse (narrow....wide) -it doesnt allow to drop
what are the 5 interactions? 1.Addictive Effects 2.Synergistic Effect 3.Antagonistic effect 4.Potentiation 5.Incompatability
Addictive effect effect of two chemicals is equal to the sum of the effect of the two chemicals taken separately. 1+1=effect
Synergistis effect 1st drug strengthens the 2nd drug
Antagonistic effect effects absorption of meds.ex: grapefruit decreases effect of med/drug
Potentiation 2nd drug enhances drug
Incompatability a situation in which two or more of the ingredients of a drug interact chemically, with resulting deterioration of the mixture.
What are the Nursing Implication? 1.Assess pt response to the therapy-most accurate source of info. patient best in response to therapy 2.holding meds/think on ur feet 3.lab result-serum level konw what drug does 4.baseline function prior to therapy 5.foster compliance (teach them)
Created by: grl