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bi240 antigen
grcc bi240 antigens and immune response
| Question | Answer |
|---|---|
| Antigen is a foreign substance on surface of individual cells that stimulate | immune response leading to a molecule that can react with antibodies |
| Self antigens | your immune system ignores or tolerates self cells. |
| self antigens activate and regulate | the immune response and intercellular communications. |
| self antigens are useful in detecting | changes in cell memebranes altered by viruses or cancer. |
| antigenicity | the capacity to stimulate the production of antibodies |
| antigenicity depends on | chemical structure, foreignness and complexity. |
| Antigen binding to its appropriate antibody causes | agglutination, phagocytosis, neutralization. |
| non-self antigens recognized as invader or as foreign and the response | production of antibodies and memory cells. |
| Antibody | specific protein produced in humoral response to bind with antigen. |
| autoantibody | antibodies attack self antigen; ones own body |
| Antibodys located in | thymus, lymphatic and bone marrow. |
| Thymus | site or maturation and proliferation of T lymphocytes |
| Lymphatic tissue | contains many lymphocytes...filter body fluids, removes foreign matter, immune response |
| bone marrow | source of stem cells, leukocytes, and maturation of B lymphocytes |
| neutrophils | phagocytic WBC's, non-specific defense, active in inflammatory response |
| basophils | WBC's. bind IgE, release histamine in anaphylaxis |
| Eosinophils | WBC's participate in allergic responses |
| Monocytes | WBC's migrate from teh blood into tissues to become macrophages. |
| macrophages | phagocytize foreign material, process and present foreign material to lymphocytes that initiate immune response. |
| mast cells | release chemical mediators such as histamine in CT |
| B lymphocytes (B-Cells) | Humoral immunity activated cell leads to become antibody-producing plasma cell or memory B cell. |
| plasma cells | develop from B lymphocytes, secrete specific antibodies. |
| T lymphocytes (T cells) | WBC's cell-mediated immunity |
| Cytoxic/killer T cells | destroy antigens, cancer cells, virus-infected cells |
| memory T cells | "remember" antigen and quickly stimulate immune response on re-exposure |
| helper T cells | activate B and T cells, control orlimit specific immune response |
| NK lymphocytes | Natural killer cells destroy foreign cells, virus-infected and cancer cells. |