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bi240 antigen

grcc bi240 antigens and immune response

Antigen is a foreign substance on surface of individual cells that stimulate immune response leading to a molecule that can react with antibodies
Self antigens your immune system ignores or tolerates self cells.
self antigens activate and regulate the immune response and intercellular communications.
self antigens are useful in detecting changes in cell memebranes altered by viruses or cancer.
antigenicity the capacity to stimulate the production of antibodies
antigenicity depends on chemical structure, foreignness and complexity.
Antigen binding to its appropriate antibody causes agglutination, phagocytosis, neutralization.
non-self antigens recognized as invader or as foreign and the response production of antibodies and memory cells.
Antibody specific protein produced in humoral response to bind with antigen.
autoantibody antibodies attack self antigen; ones own body
Antibodys located in thymus, lymphatic and bone marrow.
Thymus site or maturation and proliferation of T lymphocytes
Lymphatic tissue contains many lymphocytes...filter body fluids, removes foreign matter, immune response
bone marrow source of stem cells, leukocytes, and maturation of B lymphocytes
neutrophils phagocytic WBC's, non-specific defense, active in inflammatory response
basophils WBC's. bind IgE, release histamine in anaphylaxis
Eosinophils WBC's participate in allergic responses
Monocytes WBC's migrate from teh blood into tissues to become macrophages.
macrophages phagocytize foreign material, process and present foreign material to lymphocytes that initiate immune response.
mast cells release chemical mediators such as histamine in CT
B lymphocytes (B-Cells) Humoral immunity activated cell leads to become antibody-producing plasma cell or memory B cell.
plasma cells develop from B lymphocytes, secrete specific antibodies.
T lymphocytes (T cells) WBC's cell-mediated immunity
Cytoxic/killer T cells destroy antigens, cancer cells, virus-infected cells
memory T cells "remember" antigen and quickly stimulate immune response on re-exposure
helper T cells activate B and T cells, control orlimit specific immune response
NK lymphocytes Natural killer cells destroy foreign cells, virus-infected and cancer cells.
Created by: Wends1984