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bi240 immunity
grcc bi240 immunity
| Question | Answer |
|---|---|
| What is the early warning system of infection? | inflammation- redness, swelling, fever, pain. |
| What are the mediators of acute inflammation | mast cells and basophils |
| histamine is released from mast cells | increases permeability of capillaries |
| capillaries become leaky causing | accumulation of complement, enzymes and phagocytes at sites of infection. |
| Pathogens are eliminated and healing is initiated | via phagocytosis, etc |
| Complement components is activated and induce | acute inflammation |
| Complement C system triggers | histamine release from mast cells, increases vascular permeability and induces chemotaxis which triggers phagocytes towards sites of infection. |
| macrophages, neutrophils & eosinophils are now known as | mediators of acute inflammation. |
| Macrophages, neutrophils, eosinophils secrete | chemicals that are proinflammatory cytokines triggering increased vascular permeability to maintain acute inflammation. |
| phagocytosis process begins where | macrophages, dendritic cells, and polymorphonuclear leukocytes (PMN) |
| Phagocytosis engulfs | and destroys particles that don't belong in the area. |
| phagocytosis: adhesion | attachment or binding of phagocyte and pathogen using noncovalent interactions. |
| Phagocytosis: oponization | enhancement of phagocytosis due to better binding medated by complement or antibody receptors on the phagocytes surfaces. |
| ingestion (engulfment) cells take in via | pseudopodia and phagosomes |
| pseudopodia | surround the pathogen, then fuse to form a vacuole called a phagosome |
| Phagosomes are converted into phagolysosomes by | fusion with lysosomes (vacuoles containing a broad spectrum of digestive enzymes) and then break down. |
| Ingestion of bacterium happen via phagosomes as they are converted to | phagolysosomes that contain digestive enzymes that help with breakdown of bacteria. |
Created by:
Wends1984
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