click below
click below
Normal Size Small Size show me how
Chp.29
key terms
| Question | Answer |
|---|---|
| Immune system | a system of cells and tissues that acts to defend the body against foreign cells and infectious agents. |
| Immunity | the resistance to a given pathogen conferred by the activity of the immune system. |
| Pathogen | infectious agents including certain viruses, bacteria, fungi, and parasites. Many can trigger an immune response. |
| Innate Immunity | nonspecific defenses, such as physical and chemical barriers and phagocytic cells, that are present from birth and are always active. |
| Adaptive Immunity | a protective response, mediated by lymphocytes, that confers long-lasting immunity against specific pathogens. |
| Lymphocyte | a specialized white blood cell of the immune system. |
| Histamine | a molecule released by damaged tissue and during allergic reactions. |
| Inflammatory Response | an innate defense that is activated by local tissue damage. |
| Phagocyte | a type of white blood cell that engulfs and ingests damaged cells and pathogens. |
| Macrophage | a phagocytic cell that resides in tissues and plays an important role in the inflammatory response. |
| Neutrophil | a phagocytic cell in the circulation that plays an important role in the inflammatory response. |
| Natural Killer Cell | a type of white blood cell that acts during the innate immune response to find and destroy virally infected cells and tumor cells. |
| Interferon | antiviral proteins produced by virally infected cells to help protect adjacent cells from becoming infected. |
| Complement Proteins | proteins in blood that help destroy pathogens by coating or puncturing them. |
| B cells | white blood cells that mature in the bone marrow and produce antibodies during the adaptive immune response. |
| Thymus | the organ in which T cells mature. |
| T cells | white blood cells that mature in the thymus and can destroy infected cells or stimulate B cells to produce antibodies, depending on the type of T cell. |
| Lymph nodes | small organs in the lymphatic system where B and T cells may encounter pathogens. |
| Lymphatic system | the organ system that works with the immune system, allowing B and T cells to respond to pathogens. |
| Humoral Immunity | the type of adaptive immunity that fights infections and other foreign substances in the circulation and lymph fluid. |
| Helper T cell | a type of T cell that helps activate B cells during humoral responses. |
| Antigen | a specific molecule (or part of a molecule) to which specific antibodies can bind, and against which an adaptive response is mounted. |
| Plasma cell | an activated B cell that divides rapidly and secretes an abundance of antibodies. |
| Antibody | a protein produced by B cells that binds to antigens and either neutralizes them or flags other cells to destroy pathogens. |
| Cell-mediated immunity | the type of adaptive immunity that rids that body of altered (that is infected or foreign) cells. |
| Cytotoxic T cells | a type of T cell that destroys altered cells, including virally infected cells. |
| Allergy | a misdirected immune response against environmental substances such as dust, pollen, and foods that causes discomfort in the form of physical symptoms. |
| Autoimmune disease | a misdirected immune response in which the immune system mistakenly attacks healthy cells. |
| Primary response | the adaptive response mounted the first time a particular antigen is encountered by the immune system. |
| Memory cell | a long-lived B or T cell that is produced during the primary response and that is rapidly activated in the secondary response. |
| Secondary response | the rapid and strong response mounted when a particular antigen is encountered by the immune system subsequent to the first encounter. |
| Vaccine | a preparation of killed or weakened microorganisms or viruses that is given to people or animals to generate a memory immune response. |
| Antigenic drift | changes in viral antigens caused by genetic mutation during normal viral replication. |
| Antigenic shift | changes in antigens that occur when viruses exchange genetic material with other strains. |