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atyp typ antipsych
| Question | Answer |
|---|---|
| Aripiprazole (Abilify) | Third generation |
| clozapine (Cloziril) | Second generation |
| olanzapine (Zyprexa) | Second generation |
| paliperidone (Invega) | Second generation |
| quetiapine (Seroquil) | Second generation |
| resperidone (Risperdal) | Second generation |
| ziprasdone (Geodon) | Second generation |
| chlorpromazine (Thorazine) | First generation |
| thioridazine (Mellaril) | First generation |
| loxapine (loxitane) | First generation |
| molindone (Moban) | First generation |
| perphemazine (trilaphon) | First generation |
| trifluoperazine | First generation |
| thiothixene (Navene) | First generation |
| fluphenazine (Prolixin) | First generation |
| haloperidol (Haldol) | First generation |
| pimozide (Orap) | First generation |
| chlorpromazine (Thorazine)potency | Low potency |
| thioridazine (Mellaril)potency | Low potency |
| loxapine (loxitane)potency | Medium potency |
| molindone (Moban)potency | Medium potency |
| perphemazine (trilaphon)potency | Medium potency |
| trifluoperazine potency | high potency |
| thiothixene (Navene)potency | high potency |
| fluphenazine (Prolixin)potency | high potency |
| haloperidol (Haldol)potency | high potency |
| pimozide (Orap)potency | high potency |
| Low potency = | high sedation + high Ach + low EPS |
| High potency = | low sedation + low Ach + high EPS |
| anticholorinergic effects | blurred vision dry mouth decreased tearing dry nasal passages tachycardia constipation urinary hesitency |
| pisa syndrome | leaning to one side elderly particularly susceptible |
| EPS | dystonia, dyskinesia, akathisia, tardive dyskinesia |
| antiadrenergic effects | hypotension postural hypotension tachycardia decreased cardiac output |
| cardiac effects | longer qt interval fatal arrhytmias |
| endocrine effects | amenorrhea, loss of labido, galactorrhea, inc risk osteoporosis impotence, gynecomastia, low sperm count, fiminazation |
| metabolic syndrome | reduced metabolism glucose, resistance to insulin, DM2, obesity, inc lipid levels, hypertension, coagulation abnormalities |
| Neuroleptic Malignant Syndrome | hypterpyrexia, muscular ridgity, tremors, alt conciousness, autonomic dysfux, HTN, tachycardia, tachypnea, diaphoresis, incontinence. Elev CPK, myglobinurea, elv WBC. Metabolic acidosis. |
| Treatment for NMS | stop drug, administer bromocriptine mesylate (Parlodel), Dantrium, treat fever, maintain hydration, maintain vital fx |
| pseudoparkinsonism | mask like, stiff/stoop posture, shuffling gait, drooling, tremor, pill rolling |
| dystonia | contractions of tongue, face, neck, back, jaw |
| akethesia | motor inner drive restlessness tapping foot, rocking foward/backward in chair, shifting weigh |
| tardive dyskensia | protruding/rolling tongue, blowing, smaking, licking, spastic facial distortions. |
Created by:
1161798020
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