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NURS 572 - 103

Chapter 103 drugs for eye, drug drill

QuestionAnswer
most common type of glaucoma primary open angle glaucoma (POAG)
What are two mechanisms to treat glaucoma Decreased aqueous production (ABC) and Increased outflow (PP)
The classes of drugs that decrease aqueous humor production Alpha-2 agonists, Beta Blockers, Carbonic Anhydrase Inhibitors
Classes of drugs that increase aqueous outflow prostaglandins, parasympathomimetics
Drug in Alpha 2 agonist glaucoma brimonidine
Which Beta blocker drugs are more effective in treating glaucoma non-selective B1B2 are more effective, thought to be Beta-2 receptor that mediates aqueous production
What are the non-selective beta blockers for glaucoma timolol, carteolol, levobunolol, metipranolol
What is the selective Beta-1 blocker for glaucoma Betaxolol
What class is the first line agents in glaucoma treatment Beta Blockers used first
What are general side effects for ABC drugs Occular: burn, sting, hyperemia Systemic: HA, fatigue, xerostomia, cross BBB
What class of drugs considere last resort for glaucoma treatment CAI Carbonic anhydrase inhibitors
What are general ADRs for CAIs occular: burt, sting, allergy, dry Systemic: metallic taste, asthenia, paresthesias
CAIs - topical admin dorzolamide, brinzolamide
CAIs - systemic admin acetazolamide, methazolamide, dichlorphenamide
What class of drugs that increase outflow of aqueous humor are also considered by many to be a first-line treatment along with Beta Blockers? prostaglandins also considered this
Advantages of prostaglandin admin daily dosing, equally effective to beta blockers
What are most common occular s/e of prostaglandins racoon pigmentation around iris, eyelids, skin near eye. eylash growth, and the usual others
Name 3 prostaglandins latanoprost, travoprost, bimatroprost
prostaglandin 1 of 3 latanoprost
prostaglandin 2 of 3 travoprost
prostaglandin 3 of 3 bimatroprost
What is MOA of parasympathomimetic for glaucoma miosis pulls iris away from lining of sclera, opening the drain
What class is considered SECOND TO LAST resort for glaucoma parasympathomimetics
What two classes of parasympathomimetics for glaucoma direct acting cholinergics, indirect action AChE inhibitors
What are unusual occular s/e of parasympathomimetics brow ache, ciliary muscle spasm, miosis, iris pigmentation, cataracts
Name 2 direct-acting cholinergic for glaucoma pilocarpine, carbachol
Name 1 indirect acting cholinergic for glaucoma echothiophate
name 1 non-selective adrenergic rarely used for glaucoma dipivefrin
Created by: lorrelaws