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IB 140

Human Reproduction MT 1

QuestionAnswer
Androgens substances that promote the development and function of the male reproductive structures
Estrogens stimulate the maturation and function of the female reproductive structures
Progestogens cause the uterus to be secretory and supports pregnancy
Hormone Receptors Target cells for hormones have specific receptors on their cell membrane, in their cytoplasm, or on their nucleus to respond to a particular hormone molecule
Paracrines Not carried in Blood Stream Diffuse to act locally on adjacent cells with appropriate receptors
Protein and Peptide Hormone Receptors Bind to receptors embedded in the cell membrane of responsive cells GnRH, FSH, LH, PRL
Ligand A molecule that binds to a receptor
3 Domains of Protein and peptide hormone receptor Extracellular, Transmembrane, Intracellular Domain
Extracellular Domain Protein/Peptide Hormone Receptors: hormonal signal is received when ligand attaches to ligand-binding site in extracellular membrane that sticks out beyond the cell
Transmembrane Domain Anchors receptor within plasma membrane
Intracellular Domain Extension of receptor protein within the cell cytoplasm
Conformational Shape Change occurs within... ...the receptor when the hormone ligand (first messenger) binds to receptor. triggers a biochemical change in cell cytoplasm causing release of a second messenger
Signal Transduction Translation of hormone message to the interior of the cell with first messenger, causing a conformational change that triggers a biochemical change in the cell cytoplasm cause release of the second messenger.
Signal Transduction usually... turns on or off a series of enzymes which enables a few molecules of hormone to be amplified to alter thousands of molecules inside the cell
Created by: 720142293
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