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Organ pathology

Made Ridiculously Simple

SLE skin-malar rash, photosensitivity; Organs-arthritis, pleuritis, pericarditis, renal dz; Blood-hemolytic anemia, leukopenia, lymphocytopenia; Labs-antinuclear Abs, false + VDRL, confirmed by neg FTA-ABS
CREST Calcinosis; Raynud's; Esophageal dysmotility; Sclerodactyly; Telangiectasis
Systemic Sclerosis excessive fibrosis throughout body. 2 Types 1)limited=CREST, anti-centromere Abs; 2)diffuse systemic-widespread scleroderma, rapid progression, early visceral involvement, anti-Scl70 Ab
Sjogren's Syndrome immunological destruction of salivary and lacrimal glands. Sxs: dry eyes, dry mouth. SS-A/Anti-Ro Ab and SS-B/Anti-La Ab
Severe Combined immunodeficiency lymphopenia (B&T); X-linked or autosomal. SXS: death w/in 1st year.
DiGeorge's Immunodeficiency T cells absent; Sporadic. SXS: viral infections, fungal infections, tetany.
Bruton's Immunodeficiency B cells absent; X-linked. SXS: bacterial infections
Common Variable Immunodeficiency B cells present but produce few Abs; variable. SXS: bacterial infections.
IgA Deficiency low IgA; autosomal. most common congenital immunodeficiency. SXS: sinopulmonary infections, GI infections
Wiskott-Aldrich Immunodeficiency low IgM; x-recessive. SXS: bacterial infections, thrombocytopenia, eczema.
Created by: celaschiac