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Bio 203 muscular

Muscular System review

QuestionAnswer
cardiac action potential *sodium enters/depolarization to threshhold *thershold opens vgate sodium, more sodium enters *Sodium gates close, K channels open *PLATEAU
plateau is due to influx of Ca which is + ion, which flows in from ECF to ICF to this effect maintains/extends AP time by keeping cell at +20mV
repolarization of cardiac muscle occurs due to due to closure of Ca channels and K outflow when additional Vgate K channels open
smooth muscle also uses Ca from ECF to effect *digestive/urinary processes to expel
Ca blocking drugs used for anti-HTN: block Ca channels in sm musc of blood vessels --> unable to constrict, therefore vasodilation remains
Beta Blockers will decrease bp bwo decreased CO
heart can switch to anaerobic metabolism by this rxn ADP + creatine kinase --> ATP + creatine
lab test for creatine kinase tells us what if myocardial muscles have died, as evidenced by creatine generated by anaerobic metab prior to death (thereby liberating the enzyme to blood)
CK isoenzymes include sk muscle (CKmm), heart (CK MB), brain (CKbb)
cardiac muscle is loaded with these ATP producing cells mitochondria
*Troponin is released from myocardium @ death *CK released @ myocardium death heart muscle dies and these markers are present
Created by: lorrelaws
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