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molecular Genetics 2

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DNA, or deoxyribonucleic acid contains information that helps an organism develop and function.
DNA is composed of two polymers, which can be found in a helix structure, giving DNA the nickname "the double helix".
The backbone of the DNA polymers is made of sugars and phosphate groups, which are bonded together.
The four nitrogen bases are: 1. adenine (A) 2. cytosine (C) 3. guanine (G) 4. thymine (T)
Three bases (in a row) make up a codon.
During DNA Replication 1.The two original strands of DNA separate. 2.DNA polymerases add complementary nucleotides to each strand. (adenine bonds with thymine; cytosine bonds with guanine) 3.Two DNA molecules form, which are identical to the original DNA molecule.
The process of DNA replication begins with one double-stranded molecule of DNA.
The two strands of this molecule separate during replication, and DNA polymerases add complementary nucleotides to each strand.
Initiation: Enzymes bind to a DNA sequence and unzip the molecule.
Elongation As the molecule unzips, RNA nucleotides pair to complementary DNA nucleotides on one of the DNA strands. (If the DNA strand reads AGT, the new RNA strand would read UCA.)
Termination: Once base pairing is complete, the new RNA molecule (mRNA) breaks away from the DNA strands and the DNA strands re-attach.
The process of transcription occurs in the the nucleus of a cell, but the mRNA that is created travels into the cytoplasm once it is made.
A codon on the mRNA molecule attaches to a ribosome.
tRNA molecules, which each carry a specific amino acid approach the ribosome
The tRNA molecule that corresponds to the codon is the? tRNA anticodoon
The chain of amino acids continues to grow until the ribosome reaches a stop codon on the mRNA strand.
The first codon that is read on the mRNA molecule. is usually a start codon (AUG
Gene expression occurs as follows. The instructions for building a protein are found in a gene and are "rewritten" to a molecule of RNA during transcription. The RNA is then "deciphered" during translation.
Ribonucleic acid (RNA) A natural polymer that is present in all living cells and that plays a role in gene expression
Uracil One of the four bases that combines with sugar and phosphate to form a nucleotide subunit of RNA
Transcription The process of forming a nucleic acid by using another molecule as a template
Translation The portion of protein synthesis that uses the codons in mRNA molecules to specify the sequence of amino acids in polypeptide chains
A change of a gene is called a mutation.
Mutations can be harmful and cause genetic diseases such as cystic fibrosis and some forms of cancer
Mutations can be caused by radiation, exposure to toxic chemicals, through natural means during DNA replication, and so on.
Created by: t-raw15
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