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molecular Genetics 2
Words
| Question | Answer |
|---|---|
| DNA, or deoxyribonucleic acid | contains information that helps an organism develop and function. |
| DNA is composed of | two polymers, which can be found in a helix structure, giving DNA the nickname "the double helix". |
| The backbone of the DNA polymers is made of | sugars and phosphate groups, which are bonded together. |
| The four nitrogen bases are: | 1. adenine (A) 2. cytosine (C) 3. guanine (G) 4. thymine (T) |
| Three bases (in a row) make up a | codon. |
| During DNA Replication | 1.The two original strands of DNA separate. 2.DNA polymerases add complementary nucleotides to each strand. (adenine bonds with thymine; cytosine bonds with guanine) 3.Two DNA molecules form, which are identical to the original DNA molecule. |
| The process of DNA replication begins with | one double-stranded molecule of DNA. |
| The two strands of this molecule separate | during replication, and DNA polymerases add complementary nucleotides to each strand. |
| Initiation: | Enzymes bind to a DNA sequence and unzip the molecule. |
| Elongation | As the molecule unzips, RNA nucleotides pair to complementary DNA nucleotides on one of the DNA strands. (If the DNA strand reads AGT, the new RNA strand would read UCA.) |
| Termination: | Once base pairing is complete, the new RNA molecule (mRNA) breaks away from the DNA strands and the DNA strands re-attach. |
| The process of transcription occurs in the | the nucleus of a cell, but the mRNA that is created travels into the cytoplasm once it is made. |
| A codon on the mRNA molecule | attaches to a ribosome. |
| tRNA molecules, which each carry a specific amino acid | approach the ribosome |
| The tRNA molecule that corresponds to the codon is the? | tRNA anticodoon |
| The chain of amino acids continues to grow until | the ribosome reaches a stop codon on the mRNA strand. |
| The first codon that is read on the mRNA molecule. | is usually a start codon (AUG |
| Gene expression occurs as follows. | The instructions for building a protein are found in a gene and are "rewritten" to a molecule of RNA during transcription. The RNA is then "deciphered" during translation. |
| Ribonucleic acid (RNA) | A natural polymer that is present in all living cells and that plays a role in gene expression |
| Uracil | One of the four bases that combines with sugar and phosphate to form a nucleotide subunit of RNA |
| Transcription | The process of forming a nucleic acid by using another molecule as a template |
| Translation | The portion of protein synthesis that uses the codons in mRNA molecules to specify the sequence of amino acids in polypeptide chains |
| A change of a gene is called | a mutation. |
| Mutations can be harmful and cause genetic diseases such as | cystic fibrosis and some forms of cancer |
| Mutations can be caused by | radiation, exposure to toxic chemicals, through natural means during DNA replication, and so on. |