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patho 3
patho
| Question | Answer |
|---|---|
| is a disturbance in the immunologic tolerance to self-antigens. | autoimmunity |
| the most severe immediate hypersensitivity reaction | anaphylaxis |
| most but not all common allergic reactions are mediated by IgE making them ___ reactions | Type 1 |
| acting through H1 receptors contracts bronchial smooth muscles causing bronchial constriction increases vascular permeability causing edema and causes vasodilation increasing blood flow into the affected area. | Histamine |
| hypersensitivity reactions generally are characterized by the destruction or altered function of a target cell through the action of antibody against an antigen on the cells plasma membrane. | Type 2 |
| hypersensitivity include graft rejection tumor refection and the TB reaction and allergic reactions resulting from contact with substances such as poison ivy and metals. | Type 4 |
| most common complez and serious of the autoimmune disorders | SLE |
| the most characteristic autoantibodies produced in __ are against nucleic material | DNA |
| seen more in women then men | SLE |
| arthritis, vasculitis and rash, renal disease, hematologic abnormalities, and cardiovascular diseases. | SLE |
| facial rash confined to the cheeks | SLE |
| photosensitivity | SLE |
| oral or nasopharyngeal ulcers | SLE |
| serositis | SLE |
| presence of antinuclear antibody (ANA) | SLE |
| the presence of bacteria in the blood. | septicemia |
| partial or complete absence of a thymus, partial or complete absence of the parathyroid gland and structural defects in the heart. | DiGeorge Syndrome |
| in this syndrome penetrating the skin for routine blood tests, may potentially lead to fatal septicemia in the immunodeficient person. | DiGeorge Syndrome |
| a defect in B-cell development results in lower levels of circulating immunoglobulins | hypogammaglobulinemia |
| condition in which they are totally or nearly absent | agammaglobulinemia |
| deficiencies develop after birth and are not related to genetic defects. | aquired immuno deficiencies |
| deficient intake of ___ can profoundly depress both T and B cell function. | Zinc |
| disorders are caused by some form of medical treatment. | Iatrogenic |
| the best known example of an acquired dysfunction of the immune system | AIDS |
| newborns who contracted the virus from their mothers across the placenta during delivery or through the milk during breast-feeding. | AIDS |
| infect cells by binding to the surface of a target cell through a receptor and inserting their RNA into the target cell. | retroviruses |
| is an antigen on the surface of helper T cells \that acts as the primary receptor for the HIV | CD4 |
| virus causes a marked decrease in the CD4 cells. | AIDS |
| early stage symptoms include influenza, night sweats, swollen lymph glands, diarrhea or fatigue. | AIDS |