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transport II

QuestionAnswer
For endocytosis, TM cargo receptors bind to this adaptor protein AP2
For exocytosis, TM cargo receptors bind to this adaptor protein AP1
Clathrin binds to a ______ receptor
What characteristic of clathrin aids with the exocytosis process? The molecule is bent slightly
Name three functions of clathrin coats 1. transport from TGN to endosomes 2. return of proteins from endosomes 3. endocytosis
When this is activated with GTP, it causes the clathrin coat to form Arf
This process causes the clathrin coat to fall off ATP dephosphorylated to ADP
Binding of _______ to ________ initiates receptor mediated endocytosis LDL to LDL receptors
The binding of LDL causes this to form clathrin coat
When endoytosis happens, what happens on transportation to target site? clathrin coat falls off
A vesicle fuses with a _______ early endosome
What happens to LDL after it reaches the early endosome? sent to lysosome where it is broken down into free cholesterol
What happens to LDL receptor after it reaches the early endosome? Taken through transport vesicle to the cytosol again
What is the typical digestion pathway? (4 steps) early endosome; late endosome; lysosome; cytosol
How are vesicular bodies transported? Microtubules
Name 2 reactions that take place in the golgi complex 1. Trimming of N-linked sugars on proteins and addition of more sugars 2. O-linked glycosylation (threonine or serine)
Created by: neeck
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