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Psychiatric Meds.

Medications for Psychoses

QuestionAnswer
Conventional Antipyschotic Medications are used to control/treat which symptoms of psychosis? Positive Symptoms (agitation, delusions, hallucinations, tangential speech patterns)
Atypical Anti-psychotic Agents are used to control/treat which symptoms of psychosis? Positive and Negative Symptoms (Negative symptoms: social withdrawal, lack of emotion, lack of energy, flattened affect, decreased motivation, decreased pleasure in activities)
What are the Conventional Anti-psychotics? Chlorpromazine (Thorazine); Haloperidol (Haldol); Fluphenazine (Prolixin); Molindone (Moban); Loxapine (Loxitane); Thioridazine (Mellaril); Thiothixene (Navane)
What are the therapeutic uses of Conventional Anti-psychotics? Acute and chronic psychosis; schizophrenia; bipolar disorder (manic phase); tourette's syndrome; delusional and schizoaffective disorder; dementia; prevention of nausea/vomiting
What are the side/adverse effects of Conventional Anti-psychotics? Acute Dystonia (spasm of tongue, neck, face, and back); Parkinsonism (bradykinesia, rigidity, shuffling gait, drooling, tremors); Akathisia (inability to sit or stand still)
Side/adverse effects of Conventional Anti-psychotics continued... Late Extrapyramidal side effects (Tardive Dyskinesia--involuntary movements of the tongue and face, such as lip smacking. Involuntary movements of the arms, legs, and trunk)
Side/adverse effects of Conventional Anti-psychotics continued... Neuroleptic Malignant Syndrome (high fever, BP fluctuations, dysrhythmias, muscle rigidity, changes in level of consciousness, coma); Anticholinergic Effects; Orthostatic Hypotension; Sedation
Side/Adverse effects of Conventional Anti-psychotics continued... Neuro-endocrine effects (gynecomastia, galactorrhea, menstrual irregularities); Seizures; Sexual dysfunction; Skin effects (photosensitivity, contact dermatitis); Agranulocytosis; Severe dysrhythmias
Contraindications of Conventional Anti-psychotics Contraindicated in older adult clients with dementia
Interactions with Conventional Anti-psychotics Anticholinergic angents (avoid OTC meds such as sleep aids) CNS Depressants (ETOH, opioids, antihistamines) Levodopa
What are the Atypical Anti-psychotics? Risperidone (Risperdal); Olanzapine (Zyprexa); Quetiapine (Seroquel); Aripiprazole (Abilify); Ziprasidone (Geodon); Clozapine (Clozaril)
What are the therapeutic uses for Atypical Anti-psychotics? Negative and positive symptoms of schizophrenia, psychosis induced by levodopa therapy, relief of psychotic symptoms in other disorders (bipolar)
What are the side/adverse effects of Atypical Anti-psychotics? Onset of Diabetes Mellitus or loss of glucose control in clients with diabetes. Weight gain; Hypercholesterolemia (increased risk for hypertension); Orthostatic Hypotension; Anticholinergic Effects; Symptoms of agitation; Mild EPS (tremor)
Contraindications for Atypical Anti-psychotics Not used for dementia-related psychosis Avoid concurrent use of ETOH
Clozapine (Clozaril): Specific side/adverse effects: Risk for Agranulocytosis (baseline and weekly monitoring of WBC recommended) High risk of weight gain, diabetes, and dyslipidemia.
Interactions with Atypical Anti-psychotics Immunosuppressive meds (anticancer meds) Avoid CNS depressants (ETOH, opioids, antihistamines) Levodopa
Created by: j_bressette