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Micro CH 11 defs
Antimicrobial Terms
| Question | Answer |
|---|---|
| Decontamination | destruction, removal, or reduction in number of undesirable microbes |
| sepsis | The growth of microbes in tissues |
| Asepsis | Techniques that prevent the entry of microbes into sterile tissues |
| Antiseptic | chemicals applied to body surfaces to destroy or inhibit vegitative pathogens |
| Disinfection | Destruction of vegetative pathogens on inanimate objects |
| Sanitization | Cleansing technique that removes microorganisms and debris from inanimate surfaces |
| Degermation | Cleansing technique that removes microbes and debris from living tissue |
| Sterilization | The removal or distruction of all viable microbes |
| Highest Resistance | Prions; bacterial endospores, primarily in Bacillus and Clostridium |
| Moderate Resistance | Protozoan cysts; some fungal sexual spores, some viruses - naked more resistant than enveloped forms |
| Least resistance | Bacterial vegetative cells; fungal spores, and hyphae; enveloped viruses; yeasts; protozoan trophozites |
| germicide (microbicide) | any chemical agent that kills pathogenic microorganisms (living and non-living materials) |
| Bacteriostatic agents | prevent growth of bacterial on tissues or on objects |
| Microbial Death | permanent loss of reporductive capability in a bacterial cell |
| Surfacants | chemicals that work as microbial agents by lowering surgace tension of cell membrane by binding to lipid layer and penetrating internal region of cells - cell leakage |
| Thermal Death Time (TDT) | shortest length of time reqired to kill all test microbes at a specified temp |
| Thermal Death Point (TDP) | lowest temp required to kill all microbes in 10 minutes |
| Halogens | antimicrobial chemical - fluorine, bromine, chlorine, iodine - effective |
| Phenols | toxicity makes them too dangerous as antiseptics |
| Chlorhexidine | chlorine and two phenolic rings - targets cm & protein structure ; bactericidal for g+ and g- but inactive agains spores-- cleaners of choice to cx MRSA in hospitals |
| Alcohols | colorless hydrocarbons w one or more OH fx grps.. ethy and isopropyl |
| Hydrogen Peroxide | colorles, caustic |
| Aldehyde | formaldehyde |
| Gaseous | Ethylene oxide explosive |
| quats | detergents |