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nurs 140 ch 14

QuestionAnswer
acquired immunity production of antibodies and lymphocytes after exposure to an antigen
adenoids mass of lymphatic tissue in the nasopharynx
antibody protein produced by B cell lymphocytes to destroy antigens
antigen substance that the body recognizes as foreign; evokes an immune response. Most antigens are proteins or protein fragments found on the surface of bacteria, viruses, or organ transplant tissue cells
axillary nodes lymph nodes in the armpit (underarm)
B cell (B lymphocytes) Lymphocyte that originates in the bone marrow and transforms into a plasma cell to secrete antibodies. The B refers to the bursa of Fabricius, an organ in birds in which B cell differentiation and growth were first noted to occur.
cervical nodes lymph nodes in the neck region
complement system proteins in the bood that help antibodies and T cells kill their target
cytokines proteins that aid and regulate the immune response. examples are interferons and interleukins.
cytotoxic T cell T lymphocyte that directly kills foreign cells
dendritic cell specializes macrophage that digests foreign cells and helps B and T cells to mark antigens for destruction
helper T cell lymphocyte that aids B cells and cytotoxic T cells in recognizing antigens and stimulating antibody reproduction; also called CD4+ cell or T4 cell
immunity body's abilty to resist foreign organisms and toxins. This includes natural immunity and acquired immunity
immunoglobins antibodies (gamma globulins) that are secreted by plasma cells in response to the presence of an antigen
immunotherapy use of immune cells, antibodes, or vaccines to treat or prevent disease.
inguinal nodes lymph nodes in the groin region
interferons proteins (cytokines) secreted by T cells to aid and regulate the immune response.
interleukins Proteins (cytokines) that stimulate the growth of B and T lymphocytes
interstitial fluid fluid in the spaces between cells. This fluid becomes lymph when it enters lymph capillaries
lymph thin, watery fluid found within lymphatic vessels and collected from tissues throughout the body. Latin Lympha means clear spring water
lymph capillaries tiniest lymphatic vessels
lypmhoid organs lymph nodes, spleen, and thymus gland
lymph node a collection of stationary solid lymphatic tissue along lymph vessels
lymph vessel carrier of lymph throughout the body; lymphatic vessels empty lymph into veins in the upper part of the chest
macrophage large phagocyte found in lymph nodes and other tissues of the body
mediastinal nodes lymph nodes in the area between the lungs in the thoracic (chest) cavity
monoclonal antibody antibody produced in a laboratory to attack antigens and to destroy cells. useful in immunotherapy
natural immunity protection that an individual inherits to fight infection
plasma cell lymphocyte that produces and secretes antibodies. originates from B lymphocytes
right lymphatic duct large lymphatic vessel in the chest that receives lymph from the upper right part of the body
spleen organ near the stomach that produces, stores, and eliminates blood cells
suppressor T cell Lymphocyte that inhibits the activity of B and T lymphocytes. Also called a Treg (regulatory T cell)
T cell (T lymphocte) Lymphocyte that originates in the bone marrow but matures in the thymus gland; acts directly on antigens to destroy them or produce chemicals (cytokines) such as interferons and interluekins that are toxic to antigens
tolerance the ability of T lymphocytes to recognize and accept the body's own antigens as "self" of friendly, Once tolerace is established, the immune system will not react against the body
thoracic duct large lymphatic vessel in the chest that recieves lymph from below the diaphragm and from the left side of the body above the diaphragm; it empties the lymph into veins in the upper chest
thymus gland organ in the mediastinum that conditions T lymphocytes to react to foreign cells and aids in the immune response
tonsils mass of lymphatic tissue in the back of the oropharynx.
vaccination exposure of an individual to a foreign protein (antigen) that provokes an immune response. The response will destroy any cell that possesses the antigen on its surface and will protect against infection. The term comes from the Latin vacca, cow.
vaccine weakened or killed microorganisms, toxins, or other proteins given to induce immunity to infection or disease
immun/o protection
lymph/o lymph
lymphaden/o lymph node (gland)
splen/o spleen
thym/o thymus gland
tox/o poison
ana- again, anew
inter- between
candidiasis yeast-like fungus, normally present in the mouth, skin, intestinal tract, and vagina, overgrows, causing infection of the mouth (thrush), respiratory tract, and skin
cryptococcal infection (crypto) yeast-like (cryptococcus) causes lung, brain, and blood infections, pathogen is found in pigeon droppings and nesting places, air water, and soil
cryptosporidiosis parasitic infection of the gastrointestinal tract and brain and spinal cord. The pathogen is a one-celled organism commonly found in farm animals
cytomegalovirus (CMV) infection virus causes enteritis (inflammation of the intestinal tract) and retinitis. Found in saliva, semen, cervical secretions, urine, feces, blood, and breast milk, but usually causes disease only when the immune system is compromised
herpes simplex viral infection causes small blisters on the skin of the lips or nose or on the genitals. Herpes simplex virus also can cause encephalitis
histoplasmosis (histo) fungal infection caused by inhalation of dust contaminated with histoplasma capsulatum; causes fever, chills, and lung infection. Pathogen is found in bird and bat droppings
mycobacterium avium-intracellulare (MAI) complex infection bacterial disease manifesting with fever, malaise, night sweats, anorexia, diarrhea, weight loss, and lung and blood infections
pneumocystis pneumonia (PCP) one-celled organism causes lung infection, with fever, cough, and chest pain. Pathogen is found in air, water, and soil and is carried by animals. Infection is treated with trimethoprimsulfamethoxazole, antibiotics, pentamidine
toxoplasmosis (toxo) parasitic infection involving the central nervous system and causing fever, chills, visual disturbances, confusion, hemiparesis and seizures. aquired by eating uncooked lamb or pork, unpasteurizd dairy, and raw eggs or vegetables
tuberculosis (TB) bacterial disease (caused by Mycobacterium tuberculosis) involving the lungs, brain, and other organs. Signs and symptoms are fever, cough, loss of weight, anorexia, and blood in sputum
acquired immunodeficiency syndrome (AIDS) group of clinical signs and symptoms associated with suppression of the immune system and marked by opportunistic infections, secondary neoplasms, and neurologic problems
allergy abnormal hypersensitivity acquired by exposure to an antigen
lymphoma malignant tumor of lymph nodes and lymph tissues
Hodgkin disease malignant tumor of lympoid tissue in the spleen and lymph nodes. characterized by lymphadenopathy, splenomegaly, fever, weakness, and loss of weight and appetitie.
Non-Hodgkin lymphomas follicular lymphoma, large cell lymphoma. mostly B cell lymphomas and rarely T cell malignancies. Chemotherapy may cure or stop the progress of this disease
multiple myeloma malignant tumor of bone marrow cells
thymoma malignant tumor of the thymus gland
allergen substance capable of causing a specific hypersensitivity reaction in the body; a type of antigen
anaphylaxis exaggerated or unusual hypersensitivity to foreign protein or other substances
atopy Hypersensitive or allergic state involving an inherited predisposition. From the Greek word atopia, which means strangeness
CD4+ cells helper T cells that carry the CD4 protein antigen on their surface. HIV binds to CD4 and infects and kills T cells bearing this protein. AIDS patients have an inadequate number of CD4+ cells
Kaposi sarcoma malignant lesion associated with AIDS; arises from the lining of capillaries and appears as red, purple, brown, or black skin nodules
opportunistic infections infectious diseases associated with AIDS they occur because HIV infection lowers the body's resistance and allows infection by bacteria and parasites that normally are easily contained
protease inhibitor drug that treats AIDS by blocking the production of protease, a proteolyptic enzyme that helps create new viral pieces for HIV
reverse transriptase inhibitor (RTI) drug that treats AIDS by blocking reverse transcriptase, an enzyme needed to make copies of HIV
wasting syndrome weight loss, decrease, in muscular strength, appetite, and mental activity associated with AIDS
CD4+ cell count measures the number f CD4+ T cells (helper T cells) in the bloodstream of patients with AIDS
ELISA screening test to detect anti-HIV antibodies in the bloodstream
immunoelectrophoresis test that separates immunoglobulins
viral load test measurement of the amount of AIDS virus (HIV) in the bloodstream
computed tomography (CT) scan x-ray imaging produces cross-sectional and other views of anatomic structures
Created by: pammy7130
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