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PharmAppendix A&C
Drug Categories:Controlled Substances and FDA Pregnancy Risk
| Question | Answer |
|---|---|
| Schedule I (C-I) | high abuse potential; lack of accepted safety, not approved for medical use in the U.S.; i.e. heroin, THC, ecstasy, peyote |
| Schedule II (C-II) | potential for high abuse with severe physical or psychological dependence; approved for med use in U.S.; i.e. opioids such as meperidine, methadone, morphine, oxycodone, amphetamines, and cocaine |
| Schedule III (C-III) | less abuse potential than schedule II drugs; potential for moderate physical or psychological dependence; i.e. anabolic steroids, ketamine, hydrocodone/codeine compounded with an nonsteroidal anti-inflammatory drug |
| Schedule IV (C-IV) | less abuse potential than schedule III drugs; limited dependence potential; i.e. some sedatives and anxiety agents, non-opioid analgesics, "diet drugs" |
| Schedule V (C-V) | limited abuse potential; i.e. small amounts of opioid (codeine) used as antitussives or antidiarrheals, pregabalin (Lyrica) |
| Pregnancy Category A | adequate, well-controlled studies in pregnant women have not shown an increased risk of fetal abnormalities to the fetus in any trimester of pregnancy |
| Pregnancy Category B | animal studies revealed no adverse effects but no studies in women; or animal studies have shown adverse effects but studies in women do not have adverse effects |
| Pregnancy Category C | animal studies have shown adverse effects but no adequate or well-controlled studies in women; or no animal studies have been conducted and no good studies in women |
| Pregnancy Category D | studies in women show risk but potential benefits may outweigh the risk to the fetus |
| Pregnancy Category X | both animal studies and studies in women have shown risks; product is contraindicated for women planning to become pregnant or who are pregnant |
| Aloe Vera uses | inhibit infection and promote healing of minor burns and wounds; as a laxative |
| black cohosh (black snakeroot, squawroot)/Cimicifuga racemosa uses | for management of some symptoms of menopause and as an alternative to hormone replacement therapy; may be beneficial for hypercholesterolemia or peripheral vascular disease |
| Capsicum (hot peppers)/Capsicum frutescens uses | for neuralgic pain relief, bladder pain and hyperreflexia; as an antipruritic for psoriasis |
| Chamomile/ Matricaria chamomilla uses | drunk as an infusion for GI disturbances; as a sedative and as an anti-inflammatory agent |
| Cranberry/Vaccinium macrocarpon uses | to prevent UTI by acidifying the urine; lower pH also reduces the ammonia odor of urinary incontinence |
| Garlic/Allium sativum uses | to lower blood glucose cholesterol, and lipid levels; as topical antifungal |
| Ginger (ginger root, black ginger)/Zingiber officinale uses | as antiemetic, cardiotonic, antithrombotic, antibacterial, antioxidant, antitussive, anti-inflammatory, prophylaxis for nausea and vomiting; for GI disturbances, colic; to lower cholesterol |
| Green tea/Camellia sinensis uses | to reduce cancer risk, lower lipid levels, help prevent dental caries; for antimicrobial and antioxidative effects |
| melatonin uses | for insomnia; topically to protect against ultraviolet light |
| St. John's wort (Klamath weed, goatweed, rosin rose)/Hypericum perforatum uses | as an antidepressant or antiviral |
| Tea tree oil/Melalueca alternifolia uses | as topical antimicrobial, antifungal |