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*Impact of Genomics

Impact of Genomics

QuestionAnswer
Which of the following is NOT true of a maternal effect gene? It must be located on the X chromosome.
Which of the following statements about nurse cells are true? They are able to express both alleles present in the female.
Which of the following statements regarding epigenetic inheritance is FALSE? Epigenetic inheritance can temporarily affect an individual.
In dosage compensation: -An X chromosome can be inactivated. -Gene expression can be increased from a single X chromosome. -Gene expression can be reduced from a pair of X chromosomes.
Which of the following statements regarding X inactivation in mammals is FALSE? This process ensures a homogenous phenotype in heterozygotes.
You attempt to replicate the experiment shown in Fig 7.6, but an incompetent lab assistant inoculated the flasks in step 3 from entire plates rather than single clones. What result would you expect? You would see both fast and slow alleles in every sample.
A female mouse has been identified in which the vast majority of active X chromosomes were inherited from her father. Which of the following statements may explain this? The Xce allele inherited from her father is particularly weak.
A mutation in Xist which prevents binding to proteins that promote compaction would interfere with which stage of X inactivation? Spreading
Monoallelic expression of a gene: Occurs when the gene is imprinted.
A mouse heterozygous at the Igf-2 locus is dwarf and has 50% dwarf progeny when mated to a homozygous Igf-2m animal. Which statement about this animal is FALSE? The Igf-2m allele in this mouse came from its mother
Imprinted genes: Are only transmitted by one parent.
You develop an inbred strain of mice that display one of two distinct syndromes. What evidence might lead you to believe that these mice are mutant for a gene or genes affected by imprinting? All mice of the same litter have the same syndrome.
A pattern of transmission where all offspring have the same phenotype as their mother is consistent with which type of non-Mendelian inheritance? Extranuclear inheritance.
The gene dosage effect which affects eye color in fruit flies (see Chap 4) is most likely due to which phenomenon? Dosage compensation.
Both X-linked genes and extranuclear inheritance produce different results in reciprocal crosses. How can you distinguish between them? Extranuclear traits can be transmitted from an unaffected mother to an affected son.
For a trait known to be caused by a mitochondrial gene variant, there may be an occasional female that can transmit different phenotypes to her progeny on an apparently random basis. What situation might you suspect? She displays heteroplasmy for this trait.
In S. cerevisiae, mutations which cause a segregational petite phenotype: Are transmitted according to Mendelian rules.
Neutral petite mutations: Are an example of extranuclear inheritance.
Mitochondrial mutations in humans tend to affect some tissues more than others. Which is the most likely explanation? Some human tissues have higher energy demands than others.
Which piece of evidence provides the strongest support for the endosymbiosis theory? Genes in chloroplasts and mitochondrion have a high degree of similarity to bacterial genes.
Plant cells are the only cells capable of photosynthesis. False
In maternal effect inheritance, the phenotype of the mother determines the genotype of the offspring. False
Gene products produced by nurse cells are controlled by both alleles of the female. True
Any individual having only one copy of a gene is the same as any other individual having only one copy of a gene. False
In Chlamydomonas, mitochondria are inherited from one parent while chloroplasts are inherited from the other. True
Created by: cpemberton96
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