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MBB231 L9
| Question | Answer |
|---|---|
| partition coefficient | equilibrium constant for a substance dispersion between oil and water |
| what is a channel | water filled pore that allow small, hydrophailic molecules to diffuse through membrane, usually gated |
| what is a carrier | alters between 2 conformations that transfer small molecules across the membrane |
| characteristics of membrane carrier proteins | transmembrane segments, made of alpha helices, multiple membrane spanning regions |
| simple diffusion | movement of nonpolar and small molecules down the [gradient], linear nonsaturating relationship |
| passive/facilitated diffusion | spontaneous movement down a concentration gradient |
| active transport | movement against a concentration gradient at the expenditure of energy |
| what is the function of glucose transporter | transport glucose |
| how does glucose/Na+ syn-porter function? | use Na concentration to drive glucose from the gut lumen to outside |
| how does glucose/Na porter work together to bring dietary glucose into bloodstream | glucose/Na porter drive glucose into intestinal region which glucose is transported into blood via glucose transporter |
| significance of different Kt/Km values for glucose transporters | prevent liver from taking all the glucose |
| symporter and example | move in same direction: ie glucose/Na+ |
| antiporter and example | move in opposite direction: ie Na+/K+ |
| mechanism of Na+/K+ pump | move 3 Na+ out, conformation change, as Na+ leave, 2 K+ binds, change back to original form and release K+ inside cell |
| P-class pump | one or more ATP binding site, at lease one phosphorylates |
| V-class pump | >1 ATP binding site, maintains acidity |
| F-class pump | >1 ATP binding site, forms ATP |