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PHBio#12 Alzheimer's
| Question | Answer |
|---|---|
| agnosia | difficulty recognizing people and objects |
| alogia | impoverished speech and mental creativity |
| Alzheimer’s disease | a common neurodegenerative disease causing apoptosis of the hippocampal and cortical neurons associated with neurofibrillary tangles and amyloid plaque |
| amnesia | loss of memory |
| amyloid plaque | accumulations of amyloid peptide in the cerebral cortex that are associated with the pathologic diagnosis of Alzheimer’s disease |
| agnosia | difficulty recognizing people and objects |
| aphasia | difficulty understanding and using words |
| apraxia | difficulty carrying out familiar movements and tasks |
| atypical antipsychotic drugs | drugs used to treat schizophrenia that cause fewer neurologic side effects involving movement |
| avolition | loss of initiation of goal-directed activity |
| beta amyloid | a neurotoxic form of the peptide, amyloid, that is 42 amino acids long and is associated with familial forms of Alzheimer’s disease |
| caspases | a family of cysteine-dependent, aspartate-specific proteases that are associated with apoptosis in neurodegenerative diseases |
| delusions | abnormalities in inferential thinking |
| early onset Alzheimer’s disease | familial Alzheimer’s disease associated with single amino acid mutations in any of three autosomal genes causing 6-7% of all cases |
| flattened affect | blunting of emotional expression |
| hallucinations | abnormalities in perception |
| late onset Alzheimer’s disease | non familial Alzheimer’s disease associated with an abnormal allele of the gene for apolipoprotein E |
| neurofibrillary tangles | hyperphosphorylated form of tau microtubular protein that, along with amyloid plaques, is associated with the pathologic diagnosis of Alzheimer’s disease |
| schizophrenia | a major psychotic disorder characterized by loss of reality testing, delusions, hallucinations, disorganized thinking and behavior with inappropriate affect |
| tau protein | a microtubular protein that when present in an abnormal form is associated with pathologic findings of Alzheimer’s disease |
Created by:
gasiorr
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