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Microbio Lecture 17
cardiac and systemic diseases
| Question | Answer |
|---|---|
| lipid A stimulates | 1) platelet activating factor 2) tumornecrosis factor 3) interleukins |
| all three stimulants of lipid A lead to | disseminated intravascular coagulation |
| symptoms of septicemia, bacteremia, toxemia | fever, malaise, feeling of impending doom, petechiae, osteomyelitis |
| endocarditis symptoms | fever, fatigue, malaise, tachycardia |
| who is at risk for endocarditis? | people with abnormal heart structure |
| Tularemia causative agent | Francisella tularensis, gram - aerobic |
| transmission of tularemia | bite or direct contact |
| symptoms of tularemia | skin lesions, pus-infected lymph nodes, fever, chills, myalgia |
| tularemia pathogenicity | phagocytosis prevented, bacteria live inside |
| treatment of tularemia | tetracyline and streptomycin |
| yersinia pestis | causative agent of plague |
| what characterizes yersinia pestis? | gram - rod, bipolar staining |
| treatment of plague | tetracyline and streptomycin |
| treatment for yersinia pestis unique | vaccine |
| plague transmitted by humans | pneumonic plague |
| plague pathogenicity | bacteria multiply in blood stream and localize in lymph nodes |
| how does y. pestis avoid getting rid of | use adhesin to stick to human cells |
| what does y pestis do to you | causes apoptosis through type III secretion system |
| symptoms of plague | rosies and buboes |
| causative agent of lyme disease | borrelia burgdorferi |
| how to prevent lyme disease | protective clothing, remove ticks, antiseptic |
| describe lyme causative agent | gram -, microaerophilic, spirochete |
| lyme disease vector | Ixodes |
| transmission of lyme disease | six leg --> eight leg |
| early localized stage | erythema chronicum migrans, flu symptoms |
| early disseminated stage | smaller ECMs, nervous system (meningitis) cardiac abnormalities, joint pain |
| late chronic | chronic arthritis |
| treatment of lyme | penicillin or doxycycline |