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10/21/2011
Mitosis
| Question | Answer |
|---|---|
| Prokaryotes | Unicellular organisms that have one chromosome (one DNA molecule). |
| Interphase | G1,S and G2. Cells are not dividing. Diffuse chromatin fills the nucleus. |
| S phase | DNA moleucules replicate. Duplicated chromosome has 2 sister chromatids attached at the centromere. |
| Mitotic phase | Mitosis and Cytokinesis |
| Mitosis | Separation of duplicated chromosomes |
| Cytokinesis | Cell division |
| Eukaryotes | Several chromosomes in the nucleus |
| One Chromosome | one DNA molecule +proteins |
| Chromatin | DNA (partially folded) + associated Proteins in interphase |
| Five phases of mitosis | Prophase, prometaphase, metaphase, anaphase, telophase and Cytokinesis |
| Cleavage Furrow | Squeeze cell in half |
| Telophase | Nuclear envelopes reform (now 2 separate nuclei). Chromosomes partly unfold |
| Kinetochore | Region of centromere where microtubules attach |
| Metaphase | Centrosomes at opposite end of cell. Chromosomes attached to microtubules line up at metaphase plate (center of cell) |
| Prometaphase | Nuclear envelope Fragments. Mitotic spindle invades nucleus. Microtubules bind chromatids at Kinetochores |
| Sister Chromatid | One molecule of DNA |
| Asters | Short microtubule arrays extending from centrosomes |
| Prophase | Chromatin condenses into visible chromosomes. Mitotic spindles forms in cytoplasm between centriole pairs; lengthens as microtubules grow |
| Kinetochore Microtubules | Attach to chromatids |
| Non-kinetochore Microtubules | Go from centrosome toward metaphase plate; overlap |
| Metaphase | Equal and opposite forces try to pull sister chromatids to opposite spindle poles |
| Anaphase | Sister chromatids separate and are pulled toward opposite poles. Kinetochores Microtubules are shorten. Centosomes move farther aprt as non-kintochore MT's get longer and slide past each other. Spindle gets longer. |
| Cytokinesis on plant cells | Vesicles line up in cell center to form cell plate. The vesicles contain cell wall material. Vesicles fuse with each other. The cell wall material inside calesces to make a continuous plate, surrounded by membrane from the fused vesicles. |
| Cytokinesis on animal cells | Microfilaments under plasma membrane pinch in; form cleavage furrow to squeeze cell in half |
| Motor proteins | Walk along microtubules to pull chromatids |