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Nicotine
Psy315
| Question | Answer |
|---|---|
| Administration | Inhalation or Oral |
| Absorption | mucus lining of the mouth or lungs, ionizes in stomach, taken up by intestine |
| Disrtibution | concentrates in the brain at up to 5 times the blood level> sympathetic ganglia. adrenal medulla. parotid glads. stomach. thyroid. pancreas .kidneys |
| Metabolism | biotransfered rapidily in liver and some in lungs and kidneys |
| excretion | kidneys (if ph under 6 excreted, otherwise recirculated) |
| Pharm effects | -arousing or calming depenedent on titration -sympathetic reaction by NE ^ & epinohrine from the adrenals -^Hr and BP -^ blood flow to skeletal muscles - stim. vommiting and respitory centers -free ^ fatty acids -^ muscle activity in bowel -^ saliv |
| side effects | risks for caronary disese |
| advantage with low tar and nictoine cigarettes? | reduce exposure to 2 of 3 most dangeous chems in ciggs |
| deleterious se of smoking | - increase of cancer - coronary artery disease - chronice lung disesas (brochitas emphsyma) - prenatal drug effects |
| how to cut down on smoking | low t/n ciggs |
| smoking reinforcements | -benefits of nitcotine -tool for arousl/relaxation -attachment to process -avoidence of withdrawl |
| withdrawl | irrtability anxiety restlesness depression loss in concentraion drowsiness headaches tremors insomnia GI complaints |
| brochitas | inflamation fo lung passages |
| emphsyma | irreverable incras in size of lungs air spaces |
Created by:
pgalbato
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