| Question | Answer |
| Administration | Inhalation or Oral |
| Absorption | mucus lining of the mouth or lungs, ionizes in stomach, taken up by intestine |
| Disrtibution | concentrates in the brain at up to 5 times the blood level> sympathetic ganglia. adrenal medulla. parotid glads. stomach. thyroid. pancreas .kidneys |
| Metabolism | biotransfered rapidily in liver and some in lungs and kidneys |
| excretion | kidneys (if ph under 6 excreted, otherwise recirculated) |
| Pharm effects | -arousing or calming depenedent on titration
-sympathetic reaction by NE ^ & epinohrine from the adrenals
-^Hr and BP
-^ blood flow to skeletal muscles
- stim. vommiting and respitory centers
-free ^ fatty acids
-^ muscle activity in bowel
-^ saliv |
| side effects | risks for caronary disese |
| advantage with low tar and nictoine cigarettes? | reduce exposure to 2 of 3 most dangeous chems in ciggs |
| deleterious se of smoking | - increase of cancer
- coronary artery disease
- chronice lung disesas (brochitas emphsyma)
- prenatal drug effects |
| how to cut down on smoking | low t/n ciggs |
| smoking reinforcements | -benefits of nitcotine
-tool for arousl/relaxation
-attachment to process
-avoidence of withdrawl |
| withdrawl | irrtability anxiety restlesness depression loss in concentraion drowsiness headaches tremors insomnia GI complaints |
| brochitas | inflamation fo lung passages |
| emphsyma | irreverable incras in size of lungs air spaces |
