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Type II
BC3 - Type II Diabetes Info
| Question | Answer |
|---|---|
| Prevelance of Type II increased with | age > 55 |
| Type II is also prevalent in | obese people |
| In Type II, insulin is | insufficient or poorly utilized |
| Type II tends to | be heredity related |
| DM Type II produce | endogenous insulin |
| Endogenous insulin distinguishes | the difference between Type I & Type II |
| S/S of Metabolic Syndrome or Syndrome X | HTN, Elevated Insulin levels, Elevated triglycerides, Decreased HDL's, Elevated LDL's |
| Metabolic Syndrome is | Insulin resistance |
| Ways to prevent Metabolic Syndrome | lose weight, exercise regularly, stop smoking, eat a healthful diet |
| Risk factors for Syndrome X | Central obesity, sedentary lifestyle, polycystic ovary syndrome , urbanizaiton, westernization, Ethnicity, Famiy Hx, Gestational Diabetes, Increased age |
| Three major metabolic abnormalities have a role in Type II development | Syndrome X, Decreased ability of pancreas to produce insulin, inappropriate glucose production by the liver |
| Type II peripheral insulin resistance (Syndrome X) | Unresponsive insulin receptors - decreased fat, liver, muscle response to insulin; Overproduction of insulin by early but later beta cell exhaustion |
| Decrease ability of pancreas to produce insulin | Beta cells are fatigued; Impaired glucose tolerrance (IGT) or prediabetes; IGT may develop DM w/in 10 years; 16 million Americans have IGT |
| Inappropriate Glucose Production by the liver | Liver releases glucose in a haphazard manner; Does not respond to the body's needs; is not a primary factor in development of Type II |
| Associated with Type II diabetes | HHNK |
| Onset of Type II | Gradual - possibly over many years |
| Osmotic fluid and lyte loss can lead to | Hyperglycemic Hyperosomolar Non-Ketosis (HHNK) |
| HHNK | 500-1000mg/dl |