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pharmacology block 3

Ropivacaine new amide LA S-isomer does NOT block cardiac Na+ channel --> no cardiac toxicity.
lidocaine most commonly used LA. xylidine derivative, prototype for amide group. rapid onset, intermediate duration. It causes vasodilation --> formulations include epinephrine effective for most types of anesthetic blocks Type 1B antiarrhythmic
Benzocaine used topically
Procaine aka novicaine - first synthetic LA slow onset, short action, low potency most effective for infiltrative and nerve block anesthesia
cocaine good for eye surgery. systemic toxicity (NE and DA reuptake inhibition) vasoconstrictive - no need for epinephrine
Created by: erupe