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Pharm Test 3 Drugs
drugs for test 3
| Question | Answer |
|---|---|
| donepezil | ACh inhibitor; used for the treatment of Alzheimer's Disease |
| galantamine | ACh inhibitor; used for the treatment of Alzheimer's Disease |
| rivastigmine | ACh inhibitor; used for the treatment of Alzheimer's Disease |
| memantine | NMDA antagonists; used for the treatment of Alzheimer's Disease |
| L-dopa/Carbidopa | increase dopamoine synthesis; Treatment of Parkinson's Disease |
| Rasagiline | MOA-B inhibitor; treatment of Parkinson's disease |
| Apomorphine | dopamine receptor agonist; treatment of Parkinson's disease |
| Tolcapone/Entacapone | COMT inhibitor; treatment of Parkinson's Diseas |
| Selegiline | MOA-B inhibitor--low dosage is for treatment of Parkinson's Disease MOA-A inhibitor; large doses used for treatment of depression |
| amantadine | NMDA antagonist; treatment of Parkinson's disease and Influenza A (uncoating and release inhibitor) |
| chlorpromazine | typical antipsychotic; treatment of schizophrenia |
| fluphenazine | typical antipsychotic; treatment of schizophrenia |
| haloperidol | typical antipsychotic; treatment of schizophrenia and behavioral syndromes accompanied by motor disturbances |
| clozapine | atypical antipsychotic; treatment of schizophrenia |
| risperidone | atypical antipsychotic; treatment of schizophrenia and bipolar disorder |
| lithium | first-line/standard treatment for bioplar disorder |
| valproate | anticonvulsant; treatment of seizures and bipolar disorder |
| carbamezepine | anticonvulsant; treatment of seizures and bipolar disorder |
| lamotrigine | anticonvulsant; treatment of seizures and bipolar disorder |
| amitriptline | tricyclic antidepressant (TCA); treatment of depression |
| bupropion | atypical antidepressant; treatment of depression |
| mirtazapine | atypica depressant; treatment of depression and insomnia |
| venlafaxine | 5-HT/NE reuptake inhibitor (SRNI) treatment of depression |
| fluoxetine | serotonin selective reuptake inhibitor (SSRI); treatment of depression |
| paroxetine | serotonin selective reuptake inhibitor (SSRI); treatment of depression |
| sertraline | serotonin selective reuptake inhibitor (SSRI); treatment of depression |
| alprazolam | benzodiazepine (anxiolytic); treatment of anxiety |
| diazepam | benzodiazepine (anxiolytic); treatment of anxiety and skeletal muscle relaxtion and status epiepticus |
| buspirone | non-benzodiazepine (anxiolytic); treatment of anxiety |
| propranolol | non-benzodiazepine (anxiolytic (copletivitie Beta 1 and beta 2 blocker); treatment of performance anxiety |
| flumazenil | benzodiazepine receptor antagonist |
| temazepam | benzodiazepine for insomina |
| zaleplon | non-benzodiazepine receptor agonist for insomnia (NBRAs) |
| zolpidem | non-benzodiazepine receptor agonist for insomnia (NBRAs) |
| ramelteon | melatonin receptor agonists for insomnia |
| phenytoin | antiseizure drug |
| valproc aicd | antiseizure drug |
| phenobarbital | barbiurate; antiseizure drug |
| felbamate | glutamate receptor inhibitor; antiseizure drug |
| d-tuoburarine | non-depolarizing; nicotinic antagonists; NM blocker; skeletal muscle relaxer |
| succinylcholine | depolarizing; nicotinic antagonists; NM blocker; skeletal muscle relaxer |
| botulinum toxin | motor nerve blocker; skeletal muscle relaxer |
| baclofen | gaba analogue; skeletal muscle relaxer |
| cyclobenzaprine | skeletal muscle relaxer |
| tizanidine | alpha 2 agonists; skeletal muscle relaxer |
| dantrolene | skeletal muscle relaxer |
| oseltamivir | uncoating and release inhibitor; treatment of influenza A & B |
| acyclovir | dna replication inhibitor, purine derivatives; Treatment of Herpes simplex virus (HSV-1 & HSV-2), Epstein-Barr virus (EBV, infectious mononucleosis); Varicella-zoster virus (VZV, chickenpox); Cytomegalovirus (CMV) |
| zidovudine | RNA replication inhibitors Nucleoside Reverse Transcriptase Inhibitors Treatment OF HIV-1, HIV-2, Cytomegalovirus CMV (some) |
| nevirapine | RNA replication inhibitors Non-nucleoside Reverse Transcriptase Inhibitors Treatment of HIV-1 |
| saquinavir | RNA replication inhibitors Protease inhibitors: Peptidomimetics Treatment of HIV-1/2 |
| cyclophosphamide | Alkylating agents: Nitrogen Mustards Cell Cycle Nonspecific Drugs Treatment of Cancer: Non-Hodgkin's Lymphoma, Chronic Lymphocytic Leukemia, Acute Myeloid Leukemia, Breast, Ovarian |
| methotrexate | Antimetabolites: Folate antagonists Cell Cycle Specific Drugs Treatment of Cancer: Acute Lymphatic Leukemia, CNS leukemia (IT), Gestational Trophoblastic Neoplasia, Breast, : Non-Hodgkin's Lymphoma |
| vincristine | Natural Products--Microtubule inhibitor Cell Cycle Specific Drugs Treatment of Cancer: Huntington's Disease, : Non-Hodgkin's Lymphoma, Brain, Acute Lymphatic Leukemia |
| trastuzumab | Monoclonal antibodies Treatment of cancer: Breast (25% 1o tumors, HER2 overexpress), Prostate, Pancreatic, Lung, Ovarian |
| imatinib | Protein-tyrosine kinase inhibitors Treatment of cancer: Chronic Myeloid Leukemia (Ph+), Gastrointestinal Stromal Tumor, Acute Lymphatic Leukemia (Ph+), |
| penicillin G | Inhibitors of cell wall synthesis Therapeutic Use (Narrow Spectrum): Penicillin G – Streptococcus pneumoniae, Neisseria gonorrhea, Peptococcus magnus, Clostridium perfringens, Trepnema pallidum |
| piperacillin | Inhibitors of cell wall synthesis Therapeutic Use (Broad Spectrum, > G-): Piperacillin – Streptococcus pneumoniae, Neisseria gonorrhea, Haemophilus influenzae, Escherichia coli, Pseudomonas aeruginosa, Morganella morganii, Citrobacter freundii, etc.. |
| cefazolin | Inhibitors of cell wall synthesis Therapeutic Use (1st Generation): Cefazolin – MSSA, MSSE, Streptococcus pneumoniae, Streptococcus pyogenes, Proteus mirabilis, Escherichia coli, Klebsiella pneumoniae |
| cefeprime | Inhibitors of cell wall synthesis Therapeutic Use (4th Generation): Cefepime (gram -) – As 1st Generation, Haemophilus influenzae, Neisseria gonorrhoeae, Proteus vulgaris, Serratia marcescens, Acinetobacter calcoaceticus, Pseudomonas aeroginosa, etc.. |
| vancomycin | Inhibitors of cell wall synthesis Therapeutic UseGram (+) – MRSA, MRSE, Streptococcus pyogenes, Streptococcus pneumoniae, Corynebacterium diphtheriae, Enterococcus faecalis, Clostridium difficile |
| gentamicin | Inhibitors of protein synthesis Therapeutic Use – G- aerobes: Francisella tularensis, Klebsiella pneumoniae + Piperacillin, Enterococcus fecaelis + Ampicillin, Streptococcus agalactiae + Ampicillin |
| azithromycin | Inhibitors of protein synthesis Therapeutic Use Respiratory Tract Infections – Streptococcus pneumoniae, Haemophilus influenzae , Moraxella catarrhalis, Legionella pneumophila , Chlamydia trachomatis, Mycobacterium avium-intracellulare |
| sulfamethozazole + trimethoprim | Antimetabolites Therapeutic Use (UTI treatment) – Listeria monocytogenes, Escherichia coli, Haemophilus influenzae, Legionella pneumophilia, Proteus mirabilis, Salmonella typhi, Shigella dysenteriae, Pneumocystis jiroveci |
| levofloxacin | Inhibitors of DNA gyrase Therapeutic Use – Streptococcus pneumoniae, Escherichia coli, Bacillus anthracis, Haemophilus influenzae, Legionella pneumophilia, Proteus mirabilis, Shigella dysenteriae, |
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