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Endocrine Curr 6/7
Adult Health Curriculum 6 & 7
| Question | Answer |
|---|---|
| Hyperthyroidism also called... | Graves disease, exopthalmic goiter and thyrotoxicosis |
| Hyperthyroidism also called... | Graves disease, exopthalmic goiter and thyrotoxicosis |
| Hyperthyroidism | Overproduction of thyroid hormones |
| Thyroid hormones | T3 and T4; triiodothyronine and thyroxine |
| Graves diseases occurs most frequently... | In women, 20-40 years old |
| What type of disease is Graves disease? | Autoimmune |
| Exophthalmos | Bulging of the eyeballs |
| Characteristics of blood pressure and heart rate in hyperethyroid patient... | Rapid pulse, elevated blood pressure |
| Patients with Graves disease often have an intolerance to... | Heat |
| Hyperthyroidism is confirmed by... | Decrease in TSH levels and an increase in T3 and T4 levels |
| Hyperthyroidism is confirmed by... | Decrease in TSH levels and an increase in T3 and T4 levels |
| RAIU | Radioactive iodine uptake |
| Common medications for hyperthyroidism | Propylthiouricil and methimazole |
| PTU must be taken... | 3 times a day |
| Methimazole must be taken... | Once only |
| Gold standard for treating hyperthyroidism | Ablation therapy using radioactive iodine |
| Methimazole must be taken... | Once only |
| Subtotal thyroidectomy | Five sixths of thyroid is removed |
| Gold standard for treating hyperthyroidism | Ablation therapy using radioactive iodine |
| Hyperthyroidism diet | Foods high in calories, vitamins, mineral and carbohydrates |
| Subtotal thyroidectomy | Five sixths of thyroid is removed |
| Signs of internal bleeding | Restlessness, apprehension, increased pulse rate, decreased blood pressure and feeling of fullness in the neck |
| Hyperthyroidism diet | Foods high in calories, vitamins, mineral and carbohydrates |
| Carpopedal spasms | Muscle spasms in the wrists and feet |
| Carpopedal spasms | Muscle spasms in the wrists and feet |
| Serious complication after thyroidectomy | Thyroid storm |
| Serious complication after thyroidectomy | Thyroid storm |
| Hypothyroidism occurs most often... | In women 30-60 years old |
| Hypothyroidism occurs most often... | In women 30-60 years old |
| Hypothyroidism | Thyroid fails to secrete sufficient hormones |
| Hypothyroidism | Thyroid fails to secrete sufficient hormones |
| Severe hypothyroidism in adults is called... | Myxedema |
| Hypothyroid patients often have an intolerance to... | Cold |
| Congenital hypothyroidism is called... | Cretinism |
| Hypothyroid patients often have an intolerance to... | Cold |
| Decreased metabolism usually causes... | Bradycardia, decreased blood pressure and respirations, and exercise intolerance |
| Diagnosis of hypothyroidism is based on... | Physical examination and laboratory levels of TSH, T3, T4 and FT4 |
| Diagnosis of hypothyroidism is based on... | Physical examination and laboratory levels of TSH, T3, T4 and FT4 |
| Treatment for hypothyroidism | Replacement therapy |
| Medications for hypothyroidism | Levothyroxine (Levothroid, Synthroid, Levo-T, Eltroxin) |
| Medications for hypothyroidism | Levothyroxine (Levothroid, Synthroid, Levo-T, Eltroxin) |
| Hypothyroidism diet | High protein, high fiber, low calorie |
| Hypothyroidism diet | High protein, high fiber, low calorie |
| Simple Goiter also called | Colloid goiter |
| Simple goiter develops | When the thyroid gland enlarges in response to low iodine levels |
| Formation of thyroglobulin (colloid) is increased when... | The blood level of T3 is too low to signal the pituitary to decrease TSH secretion |
| Most cases of simple goiter caused by... | Insufficient dietary intake of iodine |
| Diagnosis of simple goiter is essentially based on... | Physical manifestations |
| Patients with simple goiter may complain of... | Dysphagia, hoarseness or dyspnea because of the pressure exerted on the esophagus |
| Medical management of simple goiter | Surgery if necessary and oral administration of postassium iodide and foods high in iodine |
| Cancer of the thyroid | Relatively rare malignancy |
| Cancer of the thyroid occurs more frequently in... | Whites and women |
| Manifestations of thyroid cancer include... | Firm, fixed, small, rounded, painless mass or nodule |
| Papillary thyroid cancer is suspected when.. | A thyroid scan shows a "cold" nodule |
| "Cold" nodules indicate | Decreased uptake of iodine radioisotope |
| Benign adenomas and follicular cancers... | Show "hot" nodules |
| "Hot" nodules indicate | Increased uptake of iodine radioisotope |
| Diagnosis confirmation of thyroid cancer | Thyroid needle biopsy |
| Treatment of thyroid cancer | Total thyroidectomy with lifelong thyroid replacement therapy |
| Major postoperative thyroidectomy complications | Respiratory distress, recurrent laryngeal damage, hemmorhage and hypoparathyroidism |
| Hyperparathyroidism | Overactivity of the parathyroid glands with increased production of PTH |
| Hyperparathyroidism may result from... | Chronic renal failure, pyelonephritis or glomerulonephritis |
| Hyperparathyroidism usually occurs in... | Adults between 30-70, twice as frequently in women |
| Primary clinical manfiestation of hyperparathyroidism... | Hypercalcemia |
| High levels of calcium in the blood may lead to... | Formation of kidney stones |
| Hyperparathyroidism diagnostics | Radiographic examination may show skeletal decalcification, PTH levels are increased, calcium is increased, phosphorus is decreased |
| Treatment for hyperparathyroidism | Surgical removal of one or more of the parathyroid glands |
| Hypoparathyroidism | Occurs when there is decreased PTH resulting in decreased calcium levels |
| Hypoparathyroidism is thought to be caused by... | Autoimmune or familial origin |
| Most common cause of hypoparathyroidism | Indadvertant removal or destruction of one or more of the parathyroid glands during thyroidectomy |
| Decreased levels of PTH cause... | Hyperexcitability, involuntary and uncontrollable muscle spasms and hypocalcemic tetany |
| Laboratory studies used to determine hypoparathyroidism | Decreased serum calcium and PTH with increased urinary calcium, and increased serum phosphorus with decreased urinary phosphorus |
| Other possible causes of hypocalcemia | Vitamin D deficiency, kidney failure and acute pancreatitis |
| Immediate treatment of hypoparathyroidism | IV administration of calcium gluconate or calcium chloride |
| SSKI | Potassium iodide |
| SSKI action | Blocks the release of thyroid hormone in thyroid storm and hyperthyroidism |
| SSKI side effects | Rash, metallic taste, burning in mouth or throat, GI irritation, headache, parotitis, hyperkalemia |
| What do you mix SSKI with to mask the taste? | Fruit juice |
| T3 normal level | 65-195 ng/dL |
| T4 normal level | 5-12 mcg/dL |
| Free T4 normal level | 1-3.5 ng/dL |
| TSH normal level | 0.3-5.4 mcg/dL |