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Lecture 10/14/11
Biol200
| Question | Answer |
|---|---|
| Deoxyribonucleic Acid | DNA, information |
| Ribonucleic Acid | RNA, information, energy carriers, catalysts. |
| Nucleotide (monomer) | Phosphate, Nitrogenous base, ribonucleotide. |
| Pyrimidines | Cytosine, thymine (only in DNA), uracil (only in RNA). |
| Purines | Adenine, guanine. |
| Base pairing | A-T has 2 hydrogen bonds, A-U in RNA. G-C has 3 hydrogen bonds. |
| Polymer | Strand of nucleic acid. Nucleic acids have polarity. New nucleotides always added to 3' end! |
| Making activated nucleotides | Deoxycytosine mono phosphate dCMP + ATP>ADP = dCDP +ATP>ADP = dCTP no oxygen put a (d) in front |
| Double stranded Nucleic Acid | -H bonds between strands hold them together. -Always anti-parallel. -One strand of DNA is "Complementary" to the other. |
| The Double Helix | Structure is due to the "torsion" (twisting) of phosphodiester bonds. Sugar deoxyribose phosphate |
| Chromosome | One very long DNA double helix and associated protein. In prokaryotes, usually only 1 chromosome and it is circular. In eukaryotes, linear usually many. Human has 46 (23 pairs). |
| Central Dogma | The long-accepted hypothesis that information in cells flows in one direction: DNA codes for RNA, which codes for proteins. Exceptions are now know (e.g. retroviruses). |
| Central Dogma cont. | Information transcribed from DNA to RNA (single stranded), then either functional or information translated. |
| Gene | Codes for a single RNA molecule. Only one DNA strand is used as a template for making RNA. |
| How are genes different? | Different nucleotide sequences, different lengths, and orientation. |
| Promoter | Sequence of nucleotide that indicates beginning of gene. |
| Terminator | Ending of sequence. |
| DNA | Strands are always anti-parallel. |