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Antitubercular Ch 12

Antitubercular Drugs-Ch 12 Mosbys

QuestionAnswer
What have states passed to control TB? New state laws have been passed that take aggressive action against individuals who are infected with tuberculosis and refuse to take or complete adequate drug therapy. Can be jailed.
What is the Action of antitubercular drugs Intracellular and extracellular bacteriostatic effect against M. tuberculosis
What is Chemoprophylaxis Taking a drug to prevent disease
When is chemoprophylaxis warranted When the patient is at high risk of developing active tuberculosis
How long is prophylactic treatment? 1 year
What is the drug of choice for prophylactic treatment? Isoniazid
Why is it not recommend for people over 35 to take prophylactic Isoniazid Increased risk of developing hepatitis.
What are the Adverse reactions of antitubercules medications Mild nausea, vomiting, diarrhea. Can be toxic to ears, kidneys, and liver.
What are adverse reactions of Capreomycin Headache, ototoxicity, nephrotoxicity, changes in blood cells, abnormal liver function, maculopapular rash, urticaria, muscle weakness, pain, swelling
What are adverse reactions of Ethambutol Dizziness, headache, confusion, dermatitis, adominal pain, anorexia, nausea, vomiting, joint pain and swelling, optic neuritis. Postural hypotension
How long after overdose of isoniazid do symptoms appear 30 minutes-3 hours
What are adverse reactions of Pyrazinamide Photosensitivity, rashes, diarrhea, hepatocellular damage, nausea, vomiting, gout, decreased blood clotting time, anemia
What are adverse reactions of Rifampin Drowsiness, headaches, generalized numbness, hearing loss, abdominal pain, hepatitis, nausea, sore mouth and tongue, vomiting
What are adverse reactions of streptomycin sulfate dizziness, headache, paresthesias, vertigo, anorexia, nausea, stomatitis, vomiting
What are drug reactions of antitubercular drugs Should be checked closely for drug interactions, which are very common.
Where can a tuberculosis infection develop Lungs, bones, bladder, other organs
How many drugs are used at a time to treat tuburculosis More than one to prevent drug resistance. (up to 3-4 at a time
How many times a day are medications given once a day in the morning on an empty stomach
What is the duration of treatment Minimum of 9 months, 3 months on once a day, than 9-24 months of twice weekly medication.
Can these medications be taken with milk? Yes
Created by: Peachfuzz2994
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