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Sulfonamides-ch 12
Mosby Ch. 12 Antiinfective medications
Question | Answer |
---|---|
Are sulfonamides bacteriocidal or bacteriostatic | Bacteriostatic-inhibits folic acid synthesis |
What are sulfonamides used to treat? | Acute and chronic urinary tract infections, cystitis, pyelitis, pyelonephritis. |
What organisms are treated with sulfonamides? | Streptococcus, Bacilis anthracis, chlamydia,ulcerative colitis |
What are the adverse reactions of Sulfonamides | Headache, drowsiness, fatigue, dizziness, vertigo, tinnitus, hearing loss, insomnia, peripheral neuropathy, hypothyroidism, hypoglucemia, anorexia, naysea, vomiting, stomatitis, abdominal pain, blood dyscrasias, rash, fever, pruritus, perioribital edema |
What are drug interactions of sulfonamides | Oral anticoagulants, methotrexate, sylfonylureas, thiazide diuretics, phenytoin, and uricosuric agents, PENICILLINS (less effective) |
When should sulfonamide be d/c | If urinary output is reduced or if a rash develops. |
What should patients on sulfonamides do? | Drink lots of water to avoid crystals, and avoid sun |
Can sulfonamides be given with food? | Yes-their absorption will be delayed by not reduced. Take 1 hour before or 2 hours after meals with a full glass of water |
What tests should be done before starting sulfonamides | CBC, UA, liver/kidney function tests, and once every month if on prolonged therapy. |
When should the patient on sulfonamides contact the perscriber | If no improvement of symptoms withing 2-3 days after beginning therapy |
What are the names of Sulfonamides | Sulfadiazine, sulfamethizole, sulfasalazine, sulfonamide combination vaginal product |
What is the trade name for sulfasalazine | Azulfidine |
What is the trade name for sulfonamide combo vag product | Sultrin, Triple sulfa, trysul |
What is the name of a Sulfonamide Mixture | Trimethoprim/sulfamethoxazole |
What is the trade names for Trimethoprim/sulfamethoxazole | Bactrim, Septra, sulfatrim |