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ID for CK

Infectious Disease for Step 2 CK

QuestionAnswer
PCN G, VK and benzathine covers which bugs? Viridans group strep, strep pyo, oral anerobes, syphilis, leptospira
Ampicillin and amoxicillin cover which bugs? Viridans group strep, strep pyo, oral anerobes, syphilis, leptospira, e. coli, lymes, a few other G- bacilli
Amoxicillin G - coverage? HELPS: H flu, e coli, listeria, proteus, Salmonella
PCN G, VK, and benzathins, Amox and Amp are best initial therapy for what diseases? OM, Dental infections, endocarditis prophy, lymes confined to rash/joint/CN 7, UTI in preggers, Listeria, Enterococcal infections
Penicillinase-resistant PCN: ox, clox, diclox and naf are used for what? Skin infectious (cellulitits, impetigo, erysipelas), staph endocarditis, staph meningitis, staph bacteremia, osteomyelitis and septic arthritis if sensitive, NOT for MRSA or meth resistant enterococcus
What is the side effect of Methicillin that prevents it from being used? Allergic interstitial nephritis
Pipercillin, ticarcillin, azlocillin, mezlocillin cover which bugs? Gram negative bacilli (ex: E coli, proteus, H flu, legionella, pseudamonas, enterobacter cloacae, serratia, H. pylori, salmonella enteriditis, salmonella typhi), use with b-lactamase inhibitor
Pipercillin, ticarcillin, azlocillin and mezlocillin are best initial therapy for which diseases? Cholecystitis, ascnding cholangitis, pylenophritis, bactermeia, hospital and ventilator associated pneumonia, neutropenia and fever; use with b-lactamase inhibitor
If a bug is sensitive to pipercillin, ticarcillin, azlocillin or mezlocillin, why would you not use them? Single organism infectious, use narrower spectrum, if you do use these, use with b-lactamase inhibitor
What bugs do all cephalosporins cover? Group A, B and C strep, viridans group strep, E. Coli, Klebsiella and Proteus mirabilis
What bugs are resistant to all cephalosporins? Listeria, MRSA and Enterococcus
What do you use if there is a rash allergy to penicilins? Cephalosporins
What do you use if there is anyphilaxis to penicillins? Non-beta lactam
What are the first generation cephalosporins? Cefazolin, Cephalexin, Cephradrine, Cefadroxyl
Which bugs are first generation cephalosporins used to cover? Staph (MSSA), Strep (except Enterococcus), some gram negative bacilli (NOT pseudamonas)
Which diseases are first generation cephalosporins able to cover? Osteomyelitis, septic arthritis, endocarditis, cellulitis
What are the second generation cephalosporins? Cefotetan, Cefoxitin, Cefaclor, Cefprozil, Cefuroxime, Loracarbef
What are second generation cephalosporins used to treats? Staph (MSSA), Strep (except Enterococcus), some gram negative bacilli (NOT pseudamonas), additional anerobe and more G- bacilli
What is special about Cefotetan or cefoxitin? Best initial therapy for PID in combo with Doxycyclin, increased risk of bleeding (due to depletion of prothrombin), disulfiram like reaction when used with alcohol
What is special about Cefuroxime, Loracarbef, Cefprozil, and Cefaclor? Cover resiratory infections like bronchitis, otitis media, and sinusitis
What are the third generation cephalosporins? Ceftriaxone, Cefotaxime, Ceftazidime
What is special about Ceftriaxone? First line for pneumococcus (including partially insensitive organisms) in meningitis, CAP (combo with macrolide), GC, lyme of heart or brain; can cause iadequate biliary metabolism
Who should Ceftriaxone be avoided in and why? Neonates due to impaired biliary metabolism
What is special about Cefotaxime? Superior to ceftriaxone in neonates and can be used for spontaenous bacterial peritonitis
What is special about Ceftazidime? Pseudamonal coverage
What is the fourth generation cephalosporin? Cefepime
What is special about Cefepime? Better staph coverage then 3rd, used for neutropenia and fever, and ventilator-associated pneumonia.
Created by: chavezc3