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HII Presentations

Rapid-rev presentations relevant to HII unit

QuestionAnswer
Adrenal hemorrhage, Hypotension, DIC Waterhouse-Friderichsen syndrome (meningococcemia)
Back pain, fever, night sweats, weight loss Pott’s disease (vertebral tuberculosis)
Bluish line on gingiva Burton’s line (lead poisoning)
Child with fever develops red rash on face that spreads to body “slapped cheeks” (erythema infectiosum/fifth disease: parvovirus B19)
Dark purple skin/mouth nodules Kaposi’s sarcoma (usually AIDS patients) [associated with HHV-8)
Dog or cat bite resulting in infection Pasteurella multocida
Erythroderma, lymphadenopathy, hepatosplenomegaly, atypical T cells Sezary syndrome (cutaneous T-cell lymphoma) or mycosis fungoides
Fever, chills, headache, myalgia following antibiotic treatment for syphallis Jarisch-Herxheimer reaction (rapid lysis of spirochetes results in toxin release)
Fever, cough, conjunctivitis, coryza, diffuse rash Measles (morbillivirus)
Fever, night sweats, weight loss B-cell symptoms (lymphomas)
Indurated, ulcerated genital lesions (nonpainful) chancre (primary syphilis)
Large rash with bull’s eye appearance erythema chronicum migrans from tick bite (Lyme disease: Borrelia burgdorferi)
Male child, recurrent infections, no mature B cells Bruton’s disease (X-linked agammaglobulinemia)
Painful blue fingers/toes, hemolytic anemia cold agglutinin disease (autoimmune hemolytic anemia caused by Mycoplasma pneumonia or EBV (infectious mononucleosis))
Palpable purpura, joint pain, abdominal pain (child) Henoch-Schonlein purpura (IgA vasculitis affecting skin and kidneys)
Pupil accommodates but doesn’t react Argyll-Robertson (prostitute’s) pupil (neurosyphilis)
Rash on palms and soles 2ary Syphilis, Rocky Mountain spotted fever
Red “currant jelly” sputum Klebsiella pneumonia
Red urine in the morning paroxysmal nocturnal hemoglobinuria
Renal cell carcinoma, hemangioblastomas, angiomatosis, pheochromocytoma von Hippel-Lindau disease (dominant tumor suppressor gene mutation—VHL gene on short arm of 3rd chromosome (3p26–p25)).
Retinal hemorrhages with pale centers Roth’s spots (bacterial endocarditis)
Short stature, ↑ incidence of tumors/leukemia, aplastic anemia Fanconi’s anemia (genetic)
Small irregular red spots on buccal/lingual mucosa with blue-white centers Koplik spots (measles)
Small, nontender, erythematous lesions on palms/soles Janeway lesions (infective endocarditits)
Smooth, flat, moist white lesions on genitals condylomata lata (2° syphilis)
Splinter hemorrhages in fingernails bacterial endocarditis
“strawberry tongue” scarlet fever, Kawasaki disease, toxic shock syndrome
Ulcerated genital lesions with exudates (painful) Chancroid (Haemophilus ducreyi)
Urethritis, conjunctivitis, arthritis in a male Reiter’s syndrome (reactive arthritis associated with HLA-B27)
Vasculitis from exposure to endotoxin causing glomerular thrombosis Schwartzman reaction
WBC casts in urine acute pyelonephritis
Weight loss, diarrhea, arthritis, fever, adenopathy Whipple’s disease (Tropheryma whippelii)
Constrictive pericarditis in devel. world M. tuberculosis
Death in CML blast crisis
DIC gram-negative sepsis, cancer, burn trauma
Food poisoning S. aureus, B. cereus, C. botulinum, E. coli
Gene involved in cancer p53 tumor suppressor gene
Glomerulonephritis (adults) Berger’s Disease (IgA nephropathy)
Heart valve in bacterial endocarditis mitral (rheumatic fever), tricuspid (IV drug abuse), aortic (2nd affected in rheumatic fever)
Helminth infection (US) 1. Enterobius vermicularis 2. Ascaris lumbricoides
Aortic aneurysm, ascending Tertiary syphilis
Autosplenectomy (fibrosis and shrinkage) sickle cell anemia (HbS)
Bacteremia/pneumonia (IV drug user) S. aureus
Bacteria associated with stomach cancer H. pylori
Bacterial meningitis (adults and elderly) H. influenza, N. meningitidis, S. pneumoniae
Bacterial meningitis (newborns and kids) Group B streptococcus (newborns), S. pneumoniae/N. meningitidis (kids)
Bleeding disorder with gp1b deficiency Bernard-Soulier disease (defect in platelet adhesion—receptor for vWF)
2ary bug in viral pneumonia patient Klebsiella, S. pneumoniae
Hepatocellular carcinoma Hep B and C (cirrhotic liver)
Hereditary bleeding disorder von Willenbrand's disease (low Factor VIII)
HLA-B27 Ankylosing spondylitis, Reiter's syndrome
Infection in blood transfusion Hep C
Kidney stones struvite (ammonium) = radiopaque (Proteus or Staph)
Malignancy associated with noninfectious fever Hodgkin's Lymphoma
Mitral valve stenosis Rheumatic heart disease
Myocarditis Coxsackie B
Neoplasm (KIDS) ALL
Pneumonia in AIDS pts pneumocystis jiroveci (PCP), cytomegalovirus, Mycobacterium avium-intracellulare, aspergillosis, candidiasis
Osteomyelitis in noncompromised pts S. aureus
Osteomyelitis in patients with sickle cell disease Salmonella
Osteomyelitis with IV drug abuse Pseudomonas
Patient with ALL/CLL/AML/CML ALL: child, CLL: adult>60, AML: adult>60, CML: adult 35-50
Hodgkin's disease young male (except nodular sclerosis type: female)
Pelvic inflammatory disease Neisseria gonorrhoeae (monoarticular arthritis)
Philadelphia chromosome CML (bcr-abl)
Pneumonia, hospital acquired gram-negatives (52%), MRSA (19%), Haemophilus spp. (5%)
ICU pneumonia (nosocomial) S. aureus (17.4%), P. aeruginosa (17.4%), Klebsiella & Enterobacter spp. (18.1%), H. influenzae (4.9%)
Primary bone tumor (adults) MM (multiple myeloma)
t(14;18) Follicular lymphoma (bcl-2 activations)
t(8;14) Burkitt's Lymphoma (c-myc)
t(9;22) Philadelphia Chromosome; CML (bcr-abl
Type of non-Hodgkins Diffuse large cell
UTI E. coli, S. saprophyticus
Viral encephalitis HSV
Aortic aneurysm, ascending Tertiary syphilis
Autosplenectomy (fibrosis and shrinkage) sickle cell anemia (HbS)
Bacteremia/pneumonia (IV drug user) S. aureus
Follicular lymphoma (bcl-2 activations) Follicular lymphoma (bcl-2 activations)
Burkitt's Lymphoma (c-myc) t(8;14)
t(9;22)Philadelphia Chromosome; CML (bcr-abl) t(9;22)
Type of hodgkin's nodular sclerosis (vs mixed cellularity, lymphocity predominance, lymphocytic depletion)
UTI E. coli, S. saprophyticus
Viral encephalitis HSV
Adrenal hemorrhage, Hypotension, DIC Waterhouse-Friderichsen syndrome (meningococcemia)
Indurated, ulcerated genital lesions (nonpainful) chancre (primary syphilis)
Bacteremia/pneumonia (IVDA) S. aureus
Bacteria found in GI tract Bacteroides (2nd most common is E. coli )
Epiglottitis Haemophilus influenzae type B
Heart valve (rheumatic fever) Mitral valve (aortic is 2nd)
Heart valve in bacterial endocarditis Mitral
Heart valve in bacterial endocarditis in IVDA Tricuspid
Primary bone tumor (adults) Multiple myeloma
Type of non-Hodgkin’s Follicular, small cleaved
Viral encephalitis HSV
Created by: srebeiro