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bio 122 3

chap 16 the lymphatic system

QuestionAnswer
when substances are exchanged with the blood and tissue fluid does more fluid leave the blood capillaries or return to them leave
what is the excess fluid that leaves the blood capillaries called lymph
what is the name for the fluid that is in the tissue interstitial fluid
lymphatic pathways: where do they begin in closed ended capillaries
lymphatic pathways: list the order that the lymph travels from lymph capillary to subclavian capillaires; vessels; nodes; trunk; collecting duct; subclavian vein; now is called plasma!
lymphatic pathways: when the lymph empties into the subclavian vein its name changes to what blood plamsa
lymphatic pathways: def of lymph capillaries; similar to what close ended simple squamous epithelium; blood capillaires
lymphatic pathways: lymphatic vessel- def, do they have valves? why large vessel structured like a vein; yes, there is no BP there so this controls the flows of lymph
lymphatic pathways: lymphatic trunk- def; they converge into what; they are named after what these are vessels that drain into large areas of the body; collecting ducts; parts of the body they are located
are tissue fluid and lymph the same?; why? yes; they are the same stuff just found in different places
tissue fluid: where does it come from blood plasma which leaves the cappillaries as water and dissolved substances
tissue fluid: what substance always remains in the capillaries large plasma proteins (globulins, albumins, fibronogens)
tissue fluid: what is important in osmotic pressure needed to move materials back into blood capillary plasma proteins
tissue fluid: some small proteins are able to leave the blood capillary and enter the interstitial fluid creating its own _____ pressure; this pressure forces the tissue fluid where osmotic pressure; lymph capillaries
tissue fluid: how is the epithelium of the lymph capillary unique the cells overlap eachother and act like valves so fluid can be forces inside but once in the capillary it cannot leave
function of lymph the lymph brings a lot of bacteria and other foreign material into the capillary
movement of lymph: lymph is controlled by what; the movement is similar to what other structure's movement muscular activity (breathing muscles, contraction of larger vessels), veins
def of edema acculilation of fluid in interstial space
lymph nodes: contain alot of what 2 things; structure; name the places they are located macrophages and lymphocytes (they fight bacteria); hilum (like a kidney) where BV and nerves enter and leave, lymph vessels enter anywhere and leave at hiluml cervical; axillary, inguinal, pelvic, abdominal, thoracic
lymph nodes:what is the function formation of lymphocytes and macrophages
what are the 2 lymph organs thymus and spleen
thymus: it is largest when; smallest us: when; as the thymus ages the tissue is replaced by what in children; adults; adipose orconnective tissue
thymus: it is divided into what; what type of WBC are located here lobules; lymphocytes;
thymus: the lymphocytes develop into what; what is the name for the hormone that the thymus secretes; this hormone stimulates ____ to mature where T cell lymphocytes; thymosin; stimulates the T-cells to mature outsite the thymus gland
what is the largest lymph organ the spleen
spleen: what lobules are similar to what?; what are the lobules filled with what the sinuses of the lymph nodes; blood instead of lymph
spleen: what are the 2 types of pulp white and red
spleen: where does a fetus produce RBC? why in the red pulp; a fetus does not have bone (hyaline cartilage) do that means no red bone marrow
body defense against infection: def of immunity the body's defense mechanisms against pathogenic agents
nonspecific immunity : name the types species resistance, mechanical barriers, chemical barriers, inflammation, phagocytosis, fever
nonspecific immunity : what is the 1st line of defense species resistance, mechanical barriers
nonspecific immunity : what is the 2nd line of defense chemical barriers, inflammation, phagocytosis, fever
nonspecific immunity :def of chemical barriers; ex enzymes are present in various body fluids that can destroy pathogens; pepsin in stomach, tears, interferons, densins
chemical barriers: def of interferons a group of hormone like peptides produced by cells in response to the presence of viruses or certain tumors that interferes with the reproduction of a virus
chemical barriers: interferons stimulate what phagocytosis and enhance the activity of cells that resist infections and the growth of tumors
chemical barriers: def of inflammation tissue response to infection and injury helps prevent spread of pathogens
chemical barriers: def of fever a nonspecific defense that begins as a viral or bacterial infection stimulates lymphocytes to proliferate, producing cells that secrete a substance called interleukin; this increase temp
def of specific immunity the resistance to specific pathogens or to their toxins or metabolic by product, it involves lymphocytes and monocytes
antigens: early in life cells learn to identify self, so any that comes into the body is identified as what nonself;
antigens: the T and B lymphocytes have what on their surface that do that receptors that recognize the foreigners and initiate antibodies to destroy them
antigens: haptens- def; how are they able to initiate an immune response molecules to small to initiate an immune response; they bind to a larger molecules that then will initiate the immune response
T lymphocytes aka thymus derived lymphocytes
antibodies: def antibodies are soluable globular proteins called immunoglobulins that account for the gamma globulins of plasma proteins- that light chains and heavy chains
antibodies: the light and heavy chains are made of what amino acids
types of immunoglobulins: aka; name the five types; they are determined by what ; the type of immunoglobulin dermines what antibodies; IgG, IgA, IgM, IgD, IgE; the amino acid sequence on its free end; how the antigen will be destroyed
allergic reaction: occurs when an abnormal amount of _____ are produced in response to what antibodies; antigen
allergic reaction: the antibodies attach to what; and the secrete what; this causes what classic symptoms of an allergic reaction the membrane of the mast cells and basophils; histamines, prostaglandins, leukotrienes; swollen tissue, contraction of bronchial tube; contraction of intestinal muscles; increased mucous production
allergic reaction: what stops the reaction before it becomes too severe the suppressor T cells
tissue rejection reaction: the transplanted tissue is interpreted by the body as what; the body develops what reaction against the tissue; what reduces this reaction a foreign antigen; immune reaction; close donor matches and immunosuppressive drugs
def of autoimmunity when the immune system fails to distinguish self cells from nonself cells, the body's own immune system attacks and damages its tissues and organs
the epicardium has what other name visceral pericardium
what layer of the heart secretes the serous fluid the epicardium
lymphatic vessels transport excess fluid away from _______ and return it to __________ the interstitial space; blood stream
def of patheogen disease causing agents
the lymphatic capillaries parallel what other network the blood capillaries
walls of lymphatic capillaries similar to what wall blood capillaries
lacteal: where located; what is their function the lining of the small intestines; absorbs digested fats then transports fats to venous circulation
lymphatic vessels similar to what veins
lymphatic vessels: how many layers; do they have valves 3; yes
lymphatic vessels: lead to specialized _____ lymph nodes
lymphatic trunks: lumbar trunk- drains lymph from where lower limbs, lower abdominal wall, pelvic organs
lymphatic trunks: intestinal trunk- drains lymph from where abdominal viscera
lymphatic trunks: intercostal and bronchomediastinal trunk- drains lymph from where portions of the thorax,
lymphatic trunks: subclavian trunk- drains lymph from where upper limb
lymphatic trunks: jugular trunk- drains lymph from where neck and head
collecting ducts: what are the 2 thoracic and right lymphatic
collecting ducts: what one is largest the thoracic
collecting ducts: thoracic duct- where is it located; empties where; drains whtat abdomin and passes up through the diaphram; left subclavian; intestinal lumbar, intercostal trunks, left subclavian and jugular
collecting ducts: R lymphatic duct- where is it located; empties where; drains what originates in R thorax at union of right jugular; R subclavian; from upper right side of the body
after leaving the 2 collecting ducts lymph enters ____ and becomes ______` venous system; part of the plasma prior to blood returning to the R atrium
lymph formation depends on what other formation tissue fluid formation
lymph formation: filtration from the plasma exceeds what; this increases the ______ pressure; this favors the tissue fluid to mvoe to where reabsorption; tissue fluid hydrostatic pressure; favors tissue fluid movement to the lymphatic capillaries
lymph formation prevent what excess tissue fluid accumulation or edema
lymph returns all small proteins that left the blood plasma to where the blood stream
lymph capillaries: what is special about their epithelial cells they overlap but are not attached to eachother
lymph capillaries: the overlap of the epithelial cells create a flap like valves in the capillary wall, these are pushed in when; but they close when when the pressure is greater on the outside of the capillary ; close when the pressure is greater on the inside
what largely influnces the movement of lymph through the lymphatic vessels muscular activity
does lymph have a low or high hydrostatic pressure low
when does lymph flow peak ; why during exercise ; due to the skeletal muscles and pressure changes associated with breathing
lymph nodes: aka; they contain a large number of what 2 things lymph glands; lymphocytes and macrophages
structure of a lymph node: BV and nerves join it through where; lymph vessels join it where; where does BV lymph vessels and nerves leave the hilum; the convex surface; the hilum
structure of a lymph node: what enclose eahc lymph node a capsule of connective tissue with numerous fibers
structure of a lymph node: def lymph nodules ; these contain what the node is partially subdived into these; masses of dividing lymphocytes and macrophages
structure of a lymph node: what is the structural unit of the lymph node the lymph nodule
structure of a lymph node: why is a tonsil unique it is composed partially of encapsulated lymph nodules
def of pyers patches; located where aggregates of lymph nodules; mucous lining of the distal portion of the small intestines
lymph nodes: cervical- location mandible, ears, deep with in the neck, along paths of larger vessels
lymph nodes: axillary- location underarm region, drain mammary glands, thorax, and upper wall of abdomen
lymph nodes: supratrochlear- location located superficially on the medial side of the elbow
lymph nodes: inguinal- location receive lymph from the lower limbs, external genitals, lowe abdominal wall
lymph nodes: pelvic- location they follow the iliac BV, receive lymph from the lymphatic vessels of the pelvic viscera
lymph nodes: abdominal- location abdominal cavity, receive lymph from the abdominal viscera
lymph nodes: thoracic- location present in the mediastinum, trachea and bonchi; receive lymph from he thoracic viscera
lymph nodes: what are the 2 primary functions filtering potential harmful particles before returning the the bloodstream and monitoring body fluids immune surveilance
lymph nodes: what are the sites for lymphocyte production red bone marrow and the lymph nodes
thymus: def soft bilobed structure enclosed in a connective tissue capsule
spleen: location; why does it resemble a large lymph node upper left portion of the abdominal cavity; it is enclosesed in a connective tissue capsule and is divided in lobules
spleen: with the chambers it is filled with what instead of lymph blood
spleen: the red pulp contains numerous what Red blood cells with many lymphocytes and macrophages
what do macrophages do the engulf ad destroy foreign particles
the spleen filters blood just as much as what filters lymph the lymph node
defense against infection: def of nonspecific defense mechanisms that are quite general and protect against many types of pathogens, they function is the same way regardless of the invader that enters
defense against infection: def of specific defense ; aka a more direct response carried out by a specialized lymphocyte that recognizes foreign molecules in body; immunity
defense against infection: nonspecific- species resistance- def; a given kind of organism develops disease that are unique to it and it is resistant to diseases that affect other species b/c it is not right environment for disease
defense against infection: nonspecific- mechanical barriers: what are they; what do they do skin mucous membrane; prevent the enterence of of some infectious agents
defense against infection: nonspecific- mechanical barriers: what happens as the skin sloughs off it removes superficial bacteria with it
defense against infection: nonspecific- mechanical barriers: what does the fluid in the mucous membrane do it washes away organisms before they become firmly attached
defense against infection: nonspecific- chemical barriers- def enzymes in body fluid
defense against infection: nonspecific- chemical barrier- what does pepsin do it has low pH due to presense of HCl the combined effect kills many pathogens
defense against infection: nonspecific- chemical barrier- what do the enzymes in tears do this enzyme, lysozyme acts against certain bacteria on the eyes
defense against infection: nonspecific- natural killer cells- aka; def NK cells; a small population of lymphocytes distinctly different from the lymphocytes that provide adaptive defense mechanisms
defense against infection: nonspecific- inflammation- what does it produce; what does the reddness result in; why do WBCs accululate at site; why does tissue fluid collect their; localized rednnes, swelling, heat and pain; BV dilation that increases blood flow and volume with in the affected tissue; they help control pthogens; they contain fibrogens do form the meshwork
defense against infection: nonspecific- phagocytosis- what does it do; def of chemotaxis; removes foreign particles from the lymph as it moves from the interstitial spaces to the blood stream; chemical released from injured tissue atract these cells
defense against infection: nonspecific- phagocytosis- what engulfs smaller particles; larger particeles neutriphils; monocytes
defense against infection: nonspecific- fever- what does it do; what substance causes it elevated body temp inhibits microbial growth and inreases phagocytic activity; interleukin-1 it raises the thermoregulatory set point in hypothalamus
defense against infection: nonspecific- fever- high body temp causes liver and spleen to stop producing what; this does what to bacteria iron; iron is needed for bacteria as temp rises and with out it they die
defense against infection: specific- immunity- an immune response is based on what ; what are the particles called that initiate the immune response the ability to distinguish self from nonself; antigens
defense against infection: specific- antigens- nonself is called what; what antigens are more likely to initiate an immune response foreign antigens; large and complex with few repeating parts
defense against infection: specific- during fetal development percursers to lymphocytes are released from red bone marrow into what 2 places thymus and stay in red bone marrow
defense against infection: specific- the percursers to lymphcytes that go the thymus specialize into what T lymphocytes/ t cells
defense against infection: specific- the precursers to lymphcytes that remain in the red bone marrow develop into what b lymphcytes
defense against infection: specific- what type of lymphocyte is 70-80% the T lymphocytes
defense against infection: specific- how do T lymphocytes respond to an antigen; how do B lymphocytes respond to an antigen attach to foreign antigen- bearing cells are have cell to cell contact; they divide and diffiantiate and produce antibodies
defense against infection: specific- the of cellular immune response when the T cells interact and attach to the antigen directly
defense against infection: specific- where is the origin of undifferentiated cells the red bone marrow
defense against infection: specific- def of helper t cell ; what happens once it is activated it is activated whne its antigen receptor combines with displayed foreign antigen; the helper t cell stimulates the B cell to produce antibodies that are specific for that antigen
defense against infection: specific- what cell is the prime target for HIV the CD4
defense against infection: specific- tcells- what does the cytotoxic cell do it recognizes nonself antigens that concerous cells or virally infected cells display .. . . more for cancer
defense against infection: specific- t cells- what does the memory t cell do these cells remember that foreign antigen and they know how to respond the next time, an differiante into cytotoxic
defense against infection: specific- Bcells- when do they become activated when it encounters an antigen whose molecular shape fits the shape of a B cells antigen receptor, then it divides
defense against infection: specific- antibody molecule- what does it look like; how many chains ; why are the heavy chains heavy a y; four chains 2 heavy and 2 light; they constist of twice the amount of amino acids as the light ones
defense against infection: specific- antibodies- how do they react in a direct attack the combine with antigens and cause them to clump or form insoluble substances
defense against infection: specific- immunoglbins- IgG- where is it found plasma and tissue fluid
defense against infection: specific- immunoglbins- IgA- where is it found exocrine gland secretions
defense against infection: specific- immunoglbins- IgM- where is it found plasma
defense against infection: specific- immunoglbins- IgD- where is it found surface of most B lymphocutes
defense against infection: specific- immunoglbins- IgE- where is it found exocrine gland secretions
immune response- def of primary plasma cells release antibodies into the lymphafter the B ad T cells become activated from an antigen
immune response- def of secondary the memory cells in future on second exposure
classifications of immunity: naturally aquired active immunity develops after a primary immune response and is a response to exposure to a live pathogen and develops s/s
classifications of immunity: artificially aquired active immunity a vaccine w/ one glycoprotein from pathogen surface is enough for foreign antigen to alert the immune system, no s/s
classifications of immunity: artificially aquired passive immunity an injection of antibodies or antitoxins, the recipients cells do not produce the antibodies
classifications of immunity: naturally aquired passive immunity immunity from mom 6 months to a year after birth (blood and breast milk, does not develop immune response
Created by: jmkettel
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