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Pharm Terms
NRN101 - Parm Test 1 -- Administration of Meds Concepts
| Front | Back |
|---|---|
| Enteral Route | Using the GI tract |
| Parenteral Route | Avoids or Circumvents GI tract (all injections & topical) |
| Troches | Pastilles or lozenges, local effect on mouth of pharynx |
| Syrup | Contain 65% sucrose and are resistant to mold, yeasts, and other microbes. |
| Elixir | Contains alcohol |
| Drug absorption rate, list slowest to fastest | Oral, Parenterally, SQ or IM, IV |
| Pharmacotherapeutics | The achievement of the desired therapeutic goal from drug therapy. The terms indications and therapeutics are synonyms |
| Pharmacokinetics | Movement of the drug particles inside the body and the processes that occur during this movement. The effect of the body on the drug. (Absorption, Distribution, Metabolism & Excretion) |
| Absorption | Movement of drug from site of administration into the bloodstream |
| Distribution | Movement of the drug through the bloodstream, into the tissues and eventually the cells |
| Metabolism | The conversion of the drug into another substance or substances |
| Excretion | The removal of the drug or what the drug became after metabolism from the body |
| Steady State | Occurs at 4-5 half-lives. When the amount of drug being absorbed equals the amount of drug being excreted |
| Pharmacodynamics | Biological, Cehmical, and Physiologic actions of a particular drug within the body and the study of how those actions occur. Essentially how the drug affects the body |
| Agonists | Promote a function |
| Antagonists | Blockers. Attach to a receptor blocking other molecules and causing an effect. |
| Anaphylaxis | Severe allergic reaction. Symptoms include: acute resp distress, marked hypotension, edema, rash, tachycardia, syanosis and pale, cool skin. Convulsions may occur. |
| Neurotoxicity: Symptoms | drowsiness, auditory and visual disturbances, restlessness, nystagmus (involuntary cyclic movement of the eyeballs) and tonic-clonic (grand mal) seizures |
| Hepatotoxicity: Symptoms | Hepatitis, jaundice, elebated liver enzyme levels and fatty infiltrations of the liver |
| Nephrotoxicity: Symptoms | Decreased urinary output, elebated BUN, increased serum creatinine, altered acid-base balance,a nd electrolyte imbalances |
| Ototoxicity: Symptoms | (Damage to the 8th cranial nerve) Tinnitus, sensorineural hearing loss. light-headedness, vertigo, spinning sensation, nausea & vomiting |
| Cardiotoxicity: Symptoms | Irregular rythms and conduction, heart failure and damage to the myocardium |
| Dosage Formula | (D/H)*Q=X |