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Biology PP16
meiosis
| Question | Answer |
|---|---|
| gametes | (eggs and sperm) contain half the complement of chromosomes found in other cells |
| fertilization | fusion of gametes |
| zygote | contains two copies of each chromosome |
| n = ? 2n = ? | 23; 46 |
| Meiosis 1 | separates the two homologs |
| meiosis II | separates the two sister chromatids |
| prophase I | chromosomes condense (coil); nuclear membrane breaks down; homologous chromosomes undergo synapsis (pair up); cross over occurs (recombination) and chromsomes exchange segments |
| metaphase I | homologous chrosome pairs line up at random at the equatorial midline; microtubules attach to centromeres |
| anaphase I | centromeres do not divide; homologs separate and move to opposite poles |
| telophas I | nuclear membrane reforms; chromosomes uncoil; after cytokinesis two haploid cells are produced |
| meiosis II | similar to mitosis but with two main differences: 1) Haploid set of chromosomes 2) Sister chromatids are not identical because of cross over |
| Prophase II | chromosomes coil; spindle forms; nuclear membrane breaks down; each chromosome is composed of two sister chromatids attached at the centromere |
| metaphase II | chromosomes line up on the midline and attach to spindle fibers |
| anaphase II | centromeres divide; sister chromatids move to opposite poles |
| telophase II | nuclear membrane reforms; chromosomes uncoil; after cytokinesis four unique haploid cells are produced. |
| synapsis | homologous chromosomes pair along their lengths in prophase I; cross over |
| reduction division | homologs separate in anaphase I reducing chromosome # to 1n- this produces haploid gametes |
| 3 key mechanism that increase genetic diversity | crossing over; independent assortment; random fertilization |
| crossing over | DNA exchanges between chromatid pairs |
| nondisjunction | members of a chromosome pair fail to separate during anaphase |
| aneuploidy | -extra chromosome or missing a chromosome |
| trisomy 21 | Down syndrome - extra chromosome at chromosome 21 |