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Biology 1210
Part 15 Mitosis
| Question | Answer |
|---|---|
| how do prokaryotic cells divide? | asexually |
| binary fission | the cell divides into 2 cell |
| why is cell division in eukaryotes more complext than in prokaryotes? | because eukaryotic contain more DNA; eurkaryotic DNA is packaged differently. |
| can eurkaryotes divide asexually? | yes. |
| name the phases of interphase | G1 phase, S phase, G2 phase. |
| G1 phase | primary growth phase |
| S phase | DNA replication |
| G2 phase | microtubule synthesis |
| M phase (Mitosis) | chromosomes pull apart |
| C phase (Cytokinesis) | cytoplasm divides |
| diploid cells | have homologous chromosomes (aka homologs) |
| homologous chromosomes (homologs) | 2 similar chromosomes |
| have many chromosomes does human have? how many homologs? | 46 chromosomes and 23 pairs of homologs |
| histones | positively charged proteins that DNA wraps around |
| what do nucleosome (bead) consist of? | 200 nucleotides of DNA and histones |
| chromatin | coiled DNA |
| name an emergent property of DNA | the strands of the double helix are complementary (A-T, C-G) so an exact copy of DNA can be made |
| mitosis mades identical (blank) 2n cells | diploid |
| meiosis makes (blank) 1n gametes | haploid |
| mitosis occurs where? | in somatic (non reproductive) cell |
| where do meiosis occur? | in germ (reproductive) cells; results in the production of gametes |
| what is mitosis reproduction use for? | developmet; growth and cell replacement; asexual reproduction |
| What are the phases in M phase? | prophase; metaphase; anaphase; telophase |
| C phase (cytokenesis) | cytoplasm divides |
| cleavage furrow | pinches the cell in two |
| cell plate | divide the cell |
| how many cell division can human cells undergo? | about 50 |
| which cells can divide endlessly? | cancer cells and stem cells |
| G1 checkpoint | cell growth is assessed |
| G2 checkpoint | DNA replication is assessed |
| M checkpoint | mitosis is assessed |
| G0 | extended rest period |
| name the 2 classes of growth-regulating genes | proto-oncogenes and tumor-supressor genes |
| proto-oncogenes | encode proteins that simulate cell division |
| tumor-suppressor genes | encode proteins that inhibit cell division |
| p53 protein | monitors the integrity of DNA; if DNA is damaged, the protein halts cell division and simulates repair enzymes; tells cells to destroy themselves if damaged beyond repair. |
| What if p53 is mutated? | cancerous cells repeatedly divide, no stopping at the G1 checkpoint |