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JM Cardiac Drugs

Antilipemic

QuestionAnswer
What are HMB-CoA reductase Inhibitors Action/indications? Reduce cholesterol levels
What medical interventions may be done with MI? Thrombolytic agents, WITHIN 1-4 HRS of MI, intraaortic balloon pump (IABP) to improve myocardial perfusion.
What meds are often prescribed for MI? Nitrates, Beta-blockers, CCB, Aspirin, and Antiplatelet aggregates.
Name 4 types of Antilipemic drugs. Bile Sequestrants;HMG-CoA Reductase Inhibitors (statins);Fibric Acid Derivatives;water-soluble vitamins.
Name 4 Bile Sequestrants. Colestipol HCL (Colestid);Colesevelam (Welchol);Cholestyramine (Questran).
What are the actions/indications for Bile Sequestrants? Treat type IIA hyperlipidemia (hyper-cholesterolemia) when dietary changes fail.
What are possible side effects for Bile Sequestrants? Ab pain, N/V,distention, flatulence,belching,N/V,constipation, reduced absorption of lipid-soluble vits:ADEK, ALTERATION IN ABSORPTION OF OTHER ORAL MEDS.
Discuss nursing implications for bile sequestrants. Teach pt to mix powder forms w/adequate liquid or fruits high in moistur to prevent accidental inhalation or esophageal distress, MONITOR PT TIMES, assess for visual changes&rickets,ADMIN OTHER ORAL MEDS 1 HR BEFORE OR 6 HOURS AFTER
Name HMG-CoA Reductase Inhibitors (statins). Atorvastatin (Lipitor),Fluvastatin (Lescol),Pravastatin (Pravachol),Simvastatin (Zocor),Lovastatin (Mevacor)
What does HMG-CoA Reductase do? Basically controls the rate of cholesterol produced.
What do HMG-CoA Reductase Inhibitors (statins) do? Used to lower cholesterol levels.
Discuss possible side effects of HMG-CoA Reductase Inhibitors. Similar to bile sequestrants, May elevate liver enzymes, may elevate liver enzymes,hepatitis or pancreatitis, rhabdomyolysis.
Discuss nursing implications for HMG-CoA Reductase Inhibitors (statins). Obtain liver enzymes baseline and monitorQ6mos,monitor CPK levels,teachavoid grapefruit,INSTRUCT PT TO REPORT ANY MUSCLE TENDERNESS,timing with/without food varies with drug.
Why monitor CPK levels with HMG-CoA Inhibitors (statins)? Could indicate muscle damage.
What are Fibric Acid Derivatives used for? What type of drug are they? Antilipemic; Used w/diet changes to lower elevated cholesterol and triglycerides.
Discuss side effects of fibric acid derivatives. Ab and epigastric pain;diarrhea(mostcommon);N/V,flatulence,heartburn,dyspepsia,
gallstones,Tridor:weak,fatigue,HA,MYOPATHY
Discuss nursing implications for fibric acid derivatives. baseline labs: LFT,CBC,electrolytes;monitor q3-6mos;administer;Lopid 30 min
BEFORE breakfast and dinner;Tricor: WITH meals.
Name three Fibric Acid Derivatives. Gemifibrate (Lopid);
Fenofibrate (Tricor); Clofibrate (Claripex).
What are water-soluble vitamins used for? Large doses decrease lipoprotein and triglyceride synthesis and increase HDL.
Name two water-soluble vitamis. Niacin (Niaspan); Nicotini acid (Nicobid)
What are side effects of water-soluble vitamins? Flushing/face/neck;pruritus,HA/orthostatic hypotension;
(ER form):hepatotoxicity;hyperglycemia;hyperuricemia,
upper GI distress
Discuss nursing implications for water-soluble vitamins. Give w/milk/food;change positions slowly;pt taking extended release (ER)-REPORT DARKENED URINE, LIGHT-COLORED STOOLS,ANOREXIA,YELLOWING OF EYES OR SKIN, SEVERE STOMACH PAIN
Created by: 100000255019352
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