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thirteenone
13-1
| Question | Answer |
|---|---|
| What ages does precocious puberty occur in males and females? | precocious puberty is defined as <9yo in males, <8yo in females |
| difference btwn true and pseudo-precocious puberty in females | true: early activation of pituitary, etc (raised GnRH, FSH, LH). pseudo: autonomous secretion of sex hormones peripherally |
| MCC of precocious puberty in males v females | males: adrenal hyperplasia. females: true (pituitary axis activation) |
| LH/FSH raised in precocious puberty implies... | central (true) precocious puberty |
| low LH/FSH in precocious puberty implies.... | pseudo-precocious (i.e. peripheral sex hormone release) |
| Rx of true vs psuedo-precocious puberty? | true= GnRH steady stream (induce menopause). pseudo= surgical removal of source [no treatment if near puberty] |
| CAH treatment | cortisol replacement |
| Fixed phase of menstrual cycle? | luteal (2nd half...14days) |
| mid-cycle pain (not at time of menstruation...rather, about 2 weeks after) | Middlesmurtz...normal peritoneal irritation |
| ovarian estrogen is called? placental? | estradiol. placental= |
| hCG is secreted by what structure after implantation? What is it's purpose? | from endometrium...purpose is to simulate LH, therefore maintaining corpus luteum..which secretes progesterone |
| Corpus luteum secretes what hormone? When does it stop | progesterone (under stimulation of hCG from endometrium)....after 8-12 weeks it stops and placenta takes over |
| paradoxical cardiac affect of HRT in menopause? | it improves lipids, but still causes increased cardiac and stroke risk |
| menopause stress incontinence treatment? | kegels + estrogen cream |
| Rx of hot flashes in menopause? | SNRIs, clonidine (a2 agonist), GABAs. NO ESTROGENS IF BREAST CA RISK |
| OCP affect on endometrial ca risk vs ovarian ca risk? | endometrial risk goes UP (due to increased estrogen). Ovaran ca risk goes down (due to no ovulation) |
| OCP is c/i in what patients | smokers >35yo, DUB, migraine, liver dz, HTN, DVT history |
| best contraceptive during breast feeding? | progestin only. Must take at same time everyday |
| What is the 3m injection you use in mentally retarded pt's who need contraception | medroxyprogesterone injxn |
| Emergency contraception options? | OCP x5, levoprogestrol (progestin) up to 120h after, copper IUD, Mifepristone (RU-486) |
| What has a higher DVT risk than OCP? | the Patch |