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11-2
| Question | Answer |
|---|---|
| common symptom of osteoperosis | vertebral micro fractures (kyphosis) |
| How do you diagnose osteoperosis? | DEXA of hip and lumbar spine |
| Raloxifene (estrogen modulator for osteoperosis) increases risk of....... | DVT (Tamoxifene for breast ca raises risk of Endo Ca) |
| joint aspirate in gout may contain WBCs. what other weird thing might happen on labs | uric acid levels can be normal |
| treatment of acute gout attack? what drug is never given? | NSAID, colchicine (can cause diarrhea), steroids. NEVER ASA (causes increased uric acid in kidney) |
| chronic gout attack rx? | probenecid (lowers uric acid r/a in kidney). or allopurinol (lowers uric acid production) |
| what sign pretty much rules out pseudogout? | podagra (confirms regular gout) |
| when do you treat pagets? | only if symptomatic or wt bearing bones (give bisphosphonates) |
| OI (blue sclerae) is abnormal _______ | collagen I |
| osteopetrosis is due to impaired _________ activity | osteoclast |
| why does H/H go down in osteopetrosis? | narrow of BM cavity |
| most sensitive test for osteomyelitis? earliest test you can do? | sensitive: tagged WBC scan. earliest: MRI |
| How do you treat Lyme dz when it is in rash stage | doxycycline (amoxicillin for pregnant) 10d |
| How do you treat disseminated Lyme dz (heart, nerve, Bell's palsy...knee/encephelopathy<--very late) | ceftriaxone |
| DIP are only affected in RA/OA? | OA (Heberdens nodes...Bouchards are also OA-->PIP) |
| What antibodies are found in RA | anti-CCP (anti cyclic) |
| what gives a false + RPR | SLE |
| Anti Jo 1 antibodies signify | polymyositis or dermatomyositis |
| most specific SLE antibody | anti-Smith |
| When do you use anti-TNF (abciximab) in RA? | very severe dz (check PPD first) |
| RA with low WBCs and splenomegaly | Felty syn |
| what malignancy is ass'd with dermatomyostis? | ovarian CA |
| rash of dermatomyositis? | heliotrope or malar rash + shawl sign + grottons papules on hand dorsum (look like psoriasis) |