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U4: Respiratory Sys
| Question | Answer |
|---|---|
| Respiratory System | w/ cardiovascular system organs exchange respiratory gases between external environment and body via pulmonary ventilation, alveolar gas exchanges, transport of respiratory gas, and exchange of gas b/t systemic capillaries and tissue cells. |
| Pulmonary ventilation | "breathing"; inhalation/inspiration and exhalation/expiration |
| Respiratory System organs | nose, pharynx, larynx, trachea, bronchi, bronchioles, lungs |
| External nose | consists of nasal bone superiorly and plates of hyaline cartilage inferiorly |
| External nares/nostrils | where air enters/leaves nasal cavity |
| Nasal septum | midline divider of nasal cavity whose superior portion consists of perpendicular plate of ethmoid bone and inferior portion of vomer bone |
| Goblet cells | cells in respiratory tract mucosa that produce sticky mucus to trap bacteria, debris; cilia will move mucus to pharynx |
| olfactory mucosa | bears receptors for sense of smell; located in small patch of superior aspect of nasal cavity |
| Conchae/Turbinates | projections in lateral walls of nasal cavity; include superior & middle conchae and inferior concha |
| Palate | forms floor of nasal cavity; anterior is "hard" and posterior is "soft" and posterior uvula |
| Paranasal sinuses | found in the frontal, ethmoid, sphenoid, and maxillary bones around nasal cavity; can have rhinitis |
| Nasolacrimal ducts | drain tears from eyes into nasal cavity |
| Pharynx | the throat; mainly skeletal muscle that facilitates swallowing; 3 sections-nasopharynx, oropharynx, laryngopharynx |
| Nasopharynx | portion of pharynx posterior to nasal cavity; passageway for air; includes pharyngeal tonsil/adenoids, auditory/Eustachian/pharyngotympanic tubes |
| Oropharynx | portion of pharynx posterior to oral cavity and inferior to nasopharynx; passageway for food and air |
| Fauces | arch-like entranceway of oropharynx at junction w/ oral cavity |
| Laryngopharynx | most inferior section of pharynx; receives air and food where air enters larynx, and food enters esophagus |
| Larynx | receives air from laryngopharynx; attached to hyoid bone by ligament & continuous w/ trachea; "voice box" b/c contains true vocal cords; mainly made of pieces of cartilage-thyroid cart, cricoids cart, arytenoids cart, and epiglottis |
| Thyroid cartilage | "adam's apple," larger in males |
| cricoid cartilage | inferior to thyroid cartilage in larynx; attached to trachea |
| Arytenoid cartilage | posterior aspect of larynx; true vocal cords are anchored to them |
| Epiglottis | upper flap extension of larynx; "guardian of airways;" |
| True vocal cords/vocal folds | provide for ability to speak; attached to arytenoid cartilages via change in length |
| Laryngitis | inflammation of larynx; produces hoarseness due to swelling interfering w/ vocal cord ability to vibrate |
| Innervation of larynx | received via branch of vagus nerve and from recurrent laryngeal nerves; damage can cause signif. loss of speech ability |
| Trachea | "windpipe;" ends by dividing into two primary/main bronchi; firm due to 16-20 C-rings of hyaline cartilage; lines w/ pseudostratified ciliated columnar epithelium; layers include mucosa, submucosa, cartilage, adventitia |
| Bronchi and Bronchioles | different sized tubes that convey air to, through, and from lungs |
| Order of bronchi | primary/main bronchisecondary/lobar bronchitertiary/segmental bronchibronchiolesalveoli |
| Lungs | fills thoracic cavity except mediastinum, left is smaller than right due to cardiac notch; divided into lobes by fissures and bronchopulmonary segments; has apex and base; consists of elastic connective tissue |
| Hilus/hilum | indentation on medial surface of each lung where bronchi and blood vessels enter and exit lung |
| Cardiac notch | indentation on anterior border of left lung into which the left aspect of heart fits |
| Right lung has 3 lobes, left lung has 2 lobes | number of lobes in lungs |
| Bronchopulmonary segments | divisons of lungs; about 10 in each lung; separated by dense connective tissue; limit spread of some lung diseases due to separation |
| Serous membrane | directly covers surface of lungs; visceral pleura |
| Parietal pleura of lungs | lines walls of thoracic cavity |
| Pleural cavity | space between visceral and parietal pleura of lungs contains pleural fluid which provides lubrication needed for lungs to slide against thoracic wall |
| Pleurisy | inflammation of the pleura; often characterized by decreased production of pleural fluid causing dryness and irritation |
| Respiratory membrane/air-blood barrier | made of fused walls of alveoli and pulmonary capillaries |
| Alveolar macrophages | called dust cells; provide phagocytosis of bacteria, carbon particles, and general debris in alveoli |
| Surfactant | substance produced by some alveolar cells called Type II cells; keeps alveoli from collapsing b/t breaths. |
| Infant respiratory distress syndrome (IRDS) | premature infants suffer from this syndrome b/c surfactant is not usually present in adequate quantities |
| Pulmonary ventilation/breathing | involves inspiration and expiration, which occur w/ changes in volume that cause changes in pressure that cause air to flow |
| Inspiration events | contraction & lowering of diaphragm via phrenic nerve; contraction of external intercostals muscles; thoracic cavity volume increases, as does pleural cavity and lung volumes, which lowers lung air pressure, creating vacuum |
| Expiration events | passive process in healthy ppl; diaphragm relaxes (dome shaped); intercostal muscles relax, allowing ribs to descend; elastic fibers in lungs recoil; volume decreases in thoracic cavity, lungs, forcing out air |
| Pneumothorax | condition due to wound to chest wall w/ subsequent penetration of parietal pleura (or rupture of visceral pleura) allowing excess air to enter pleural cavity; breaks fluid bond b/t parietal & visceral pleura causing collapsed lung |
| Atelectasis | collapse of lung |
| Neural control of ventilation/breathing | phrenic & intercostal nerves contract main respiratory muscles; medulla oblongata is origin of impulses and has brain's most important respiratory center; chemoreceptors can also alter breath rate based on amt of oxy in blood |
| Chronic Obstructive Pulmonary Diseases (COPDs) | patients usually smokers, dyspnea (labored breathing) gets progressively worse, coughing & frequent pulmonary infections, hypoxia, retention of CO2, respiratory acidosis, respiratory failure; chronic bronchitis, emphysema |
| Chronic bronchitis | nearly always associated w/ smoking; severe inflammation of lower respiratory tract & excessive production of mucus which impairs ventilation, gas exchange; increased chance of lung infection, pneumonia |
| Emphysema | breakdown of alveolar walls and fibrosis in lungs; buildup of scar tissue decreases lung elasticity so expiration becomes difficult; leads to "barrel chest" |
| Lung cancer | 20x greater in smokers than non-smokers; cilia of respiratory tract become overwhelmed and stop functioning giving free radicals and carcinogens greater access to accumulate |
| Cystic Fibrosis | genetically-determined birth defect that involves over-secretion of a thick mucus that clogs respiratory passages and increases risk of fatal respiratory infections |