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Pharm/diab2
| Question | Answer |
|---|---|
| Mimics normal pancreatic insulin secretion with constant levels | Basal Insulin |
| Mimics spikes of physiologic secretion insulin after eating | Bolus Insulin |
| Rapid/Bolus | Aspart Insulin |
| Rapid/Bolus | Lisporo Insulin |
| Rapid/Bolus | Glulisine Insulin |
| Short/Bolus | Regular Insulin |
| Intermediate/Basal | NPH |
| Long/Basal | Detemir Insulin |
| Long/Basal | Glargine Insulin |
| Sulfonylureas - Stimulates pancreatic secretion of insulin (1st Gen) | Dymelor (acetohexamide) |
| Sulfonylureas - Stimulates pancreatic secretion of insulin (1st Gen) | Diabinese (chlorpropamide) |
| Sulfonylureas - Stimulates pancreatic secretion of insulin (1st Gen) | Tolinase (tolazamide) |
| Sulfonylureas - Stimulates pancreatic secretion of insulin (1st Gen) | Orinase (tolbutamide) |
| Sulfonylureas - Stimulates pancreatic secretion of insulin (2nd Gen) | Diabeta (glyburide) |
| Sulfonylureas - Stimulates pancreatic secretion of insulin (2nd Gen) | Glucotrol (glipizide) |
| Sulfonylureas - Stimulates pancreatic secretion of insulin (2nd Gen) | Amaryl (glimepiride) |
| Biguanides - Inhibits hepatic gluconeogenesis and increases insulin receptor sensitive in muscle and adipose tissues | Glucophage (metformin) |
| Thiazolidinediones- increases insulin sensitivities and decreases hepatic gluconeogenesis | Actos (pioglitazone) |
| Thiazolidinediones- increases insulin sensitivities and decreases hepatic gluconeogenesis | Avandia (rosiglitazone) |
| Alpha-glucosidase Inhibitors: inhibits enzymes in the small intestine, dealaying the breakdown of sucrose and complex CHO's.. net result in reducing postprandial hyperglycemia | Precose (acarbose) |
| Alpha-glucosidase Inhibitors: inhibits enzymes in the small intestine, dealaying the breakdown of sucrose and complex CHO's.. net result in reducing postprandial hyperglycemia | Glyset (miglitol) |
| Meglitinides- stimulates insulin release from pancreatic Beta Cells | Prandin (repaglinide) |
| Meglitinides- stimulates insulin release from pancreatic Beta Cells | Starlix (nateglinide) |
| Amylin analogs - analogs of human amylin co secreted with insulin by beta cells, reduces postprandial glucose increases | Symlin (pramlintide) |
| Incretin System- secreted after a meal from the intestine and stimulates glucose dependent insulin secretion | GLP-1 and GIP |
| Dipeptidyl peptidase-4 Inbitiors (DPP-4) Inhibits the DPP-4 enzyme resulting in prolonged active incretin level of both GLp-1 and GIP | Januvai (sitagliptin) |
| Dipeptidyl peptidase-4 Inbitiors (DPP-4) Inhibits the DPP-4 enzyme resulting in prolonged active incretin level of both GLp-1 and GIP | Onlyza (sazagliptin) |
| GLP-1 agonists : analog of the incretin hormone, GLP-1, which increase insulin secretion, increases betall cell growth and replication, slow gastric emptying and may decrease food intake (saliva of Gila monster) | Byetta (exenatide) |
| GLP-1 agonists : analog of the incretin hormone, GLP-1, which increase insulin secretion, increases betall cell growth and replication, slow gastric emptying and may decrease food intake (saliva of Gila monster) | Victoza (liraglutide) |
Created by:
Blanche40
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