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Specifc immunity U 4

Specific immunity Unit 4

QuestionAnswer
Specific Immune Response when lymphocytes are called upon to recognize foreign substances or particles and act to eliminate them
Acquired Immune response is a specific immunity that a host develops after exposure to foreign particles or produced after protection is transferred to it.
Antigen any substance that is foreign to the body that cuases the body to produce antibodies in response and combined specificially to that antibody (for every antigen we have an antibody)
Antibody a protein produced by the body in response to an antigen and combines specifically with that antigen.
Active natural aquired immunity having the chicken pox and your body producing antibodies to fight off future infection. Active-I made the antibodies, Natural-I came in contact with the antigen
Active artifical Immunity Given via injection to produce the antibodies to an infection.
Types of acquired immunity Active natural, active artifical, Passive natural, passive artifical
Natural passive immunity when a baby is born with no immune system but gets the antibodies thru breast milk
Passive artifical acquired immunity Immunoglobin shot-artifical antibodies
Types of antibodies IgM, IgG, IgA, IgD, IgE
IgM Pentamer, prodcued to measurable levels after 10-12 days but life is 5-6 days. 10 reaction sites so can neutralize rapidly, is the first responder
IgG Monomer, shows up after 14 days, life expectancy is 30 days, makes up 80% of antibodies.
IgA dimer, life span of 6 days, found in mucus membrane
IgD Monomer, found on the surface of the B-lymphocytes, insituates, the differentation of B-lymphocytes into either plasma or memory cells
IgE Monomer, found in mast (not in circulation but in tissue) cells and basophiles. THESE ARE YOUR ALLERGIES
IgE are multi-lobed, nucleated, with large basophil cells of histamine. Mast cells are in tissue. Basophil/mast cells are same thing, location different
Process of becoming allergic Allergen->helper T cells -> IgD -> B-lymphocyte -> IgE -> basophile or mast cell, you don't become allergic until the antigen is bound to the basophile and mast cell
Allergic reaction Anaphylaxis shock, cytotoxic, immune complex, delayed t-cell mediated response
Anaphylaxis shock system wide reaction degranulation where all basophiles dilate and your heart can't pump enough to keep up with fluid produced.
Cytotoxic compliment assistant the antigen will help the antibodies produce reaction
Immune complex When antibodies and a soluble antigen forms small complexes. causes inflammation (edema) in and organ in our system. causes auto immune disease
Delayed T-cell mediated response Posion ivy, TB skin test, Bee stings
Created by: tammye_miller
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