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Barrier to disease 4

Non-specific immune response

QuestionAnswer
Non-specific Immune Responses General barriers, physical barriers, chemical barriers, biological barriers
General Barriers to disease Age, Nutrition, acute phase reactant, fever, genetic factors
Age Very young are prone to disease-undeveloped immune system. Old are prone to disease-immune system is worn out.
Nutrition Malnourished are more prone to disease compared to a nourished body.
Acute Phase Reactant are changes in the host blood plasma (changes in chemistry of the blood plasma) that lead to infection or cause changes. Ex. diabetes
Fever stimulates WBCs-gets immune system active, takes the affected organ out of optimum temp range to decrease growth inhibition, ehances (kicks in) the activity of our specific acquired immunity.
Genetic Factors Humans do not get the same diseases as animals b/c human temp is 37 C. Food choices, balanced diet with minimum red meat consumption.
Zoonosis disease we can get from animals, ex. rabies.
Physical barriers skin and mucus membrane
Chemical barriers Beta-lysine and hormoones
Beta-lysine enzymes that act against invading organisms, they attack and break-down bacteria. This occurs naturally in tears and salvia.
Hormones Bacteria tends to take advantage of our hormonal imbalance. Good hormonal nature, good health.
Biological barriers Normal flora, inflammation, phagocytosis
Normal flora most areas of the body have a natural amount of microbes living in this area (naturally occuring organisms living in the body). It is harder to cause infection with this is present
Inflammation multi step process-bleeding, fever, edema, pus
pus build up of WBC's to protect again infection
Phagocytosis "eating cell" Organism is drawn to the WBC's. The process of WBC eating the organisms and digesting it. Occurs in cell membranes
Phagocytosis Chemotoxis will adhere, invagination with phagosome formation, migration, digestion (killing and breaking down cells), and dumping of residual waste.
chemotoxis things that move into the direction of chemical stimulants
Granules contain beta-lysine
Created by: tammye_miller
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