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BAMC M6 HIV/AIDS
| Question | Answer |
|---|---|
| The causative agent is a retrovirus that infects and depletes the CD4+ T-helper lymphocytes, one of the “protector” cells of the immune system. | What is the causitive agent of HIV? |
| B lymphocytes secrete antibodies into the body fluids, what kind of immunity is this?? | this is known as humoral immunity. |
| T lymphocytes can penetrate living cells what kind of immunity is this?? | a process called cell-mediated immunity. |
| Once HIV has entered the body, it attaches most efficiently to CD4+ molecules, which are predominantly located where? | on the cell membrane of T4 helper lymphocytes. |
| Body fluids known to transmit HIV are? | blood, vaginal secretions, semen, and breast milk. |
| Enzyme-linked immunosorbent assay (ELISA)— | serologic test for detecting antibody to HIV |
| Body fluids known to transmit HIV are? | blood, vaginal secretions, semen, and breast milk. |
| Western blot test—used to confirm | a positive result on ELISA |
| Highly active antiretroviral therapy (HAART) | consists of medications that belong to six different classifications because they act to prevent HIV replication at six different points along the replication process. |
| are proteins produced by B lymphocytes; they consist of two light and two heavy chains that form a Y shape. | Antibodies (or immunoglobulins) |
| Direct Coombs' test: | determines the antibody attached to the patient's RBCs. |
| Whole Blood | Consists of RBCs, plasma, plasma proteins, and approximately 60 mL anticoagulant/preservative solution in a total volume of approximately 500 mL. |
| Packed RBCs | Consist primarily of RBCs, a small amount of plasma, and approximately 100 mL anticoagulant/preservative solution in a total volume of approximately 250 to 300 mL/unit. |