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microbio275 pt. 1

Gram Negative Pathogens

largest group of human bacterial pathogens gram-negative bacteria
pathogenic gram-negative cocci neisseria
regularly causes diseases; nonmotile, aerobic bacteria, oxidase positive neisseria
adhere to genital, urinary, and digestive tract; painful urination & pus-filled discharge (men); asymptomatic & pelvic inflammatory disease (women) neisseria gonorrhoeae
normal microbiota of upper respiratory tract; transmitted in close contact; cause death within 6 hrs of symptoms neirsseria meningitidis
most common gram-negative pathogens; coliform vs non-coliform; opportunists & true pathogens Enterobacteriaceae
outer membrane, type III secretion system, capsular antigen, flagellar antigens of typical enteric bacteria
fimbria, exotoxin, adhesion, plasmid, iron-binding protein, hemolysin virulence factors of typical enteric bacteria
found in soil & plants; colonize intestinal tracts of animals and humans coliform opportunistic enterobacteriaceae
most common & important of the coliforms; virulent strains=virulent plasmids; common cause of non-nosocomial urinary tract infections Escherichia coli
capsule protects bacteria from phagocytosis, causes pneumonia Klebsiella
produce red pigment; grows on catheters & hospital supplies; can cause life-threatening opportunistic infections in immunocompromised patients; difficult treat due to resistance to antimicrobial dugs Serratia
most commonly associated with human disease: produces urease, UTI/catheters, infection-induced kidney stones, resistant to many antimicrobial drugs Proteus (mirabilis)
always pathogenic; secrete proteins that inhibit phagocytosis, rearrange the cytoskeletons of eukaryotic cells, or induce apoptosis pathogenic enterobacteriaceae
gram(-), motile bacilli, fecal-oral route, causes salmonellosis, peritonitis, & typhoid fever; fluid & electrolyte replacement Salmonella
gram(-), nonmotile, diarrhea-inducing enterotoxin, 4 well-defined species: S. dysenteriae, S. flexneri, S. boydii, S. sonnei Shigella
normal pathogen of animals, gram(-), facultatively anaerobic bacilli Yershinia
causes inflammation of intestinal tract Y. enterocolitica
similar to y. enterocolitica but less severe Y. pseudotuberculosis
causes bubonic and pneumonic plague; antibacterial drugs are effective Y. pestis
normal; humans infected by animal bites/inhalation of aerosols;antibacterial drugs are effective Pasteurellaceae
capsules resist phagocytosis,can be sexually transmitted (Pasteurellaceae) Haemophilus
small, nonmotile, aerobic coccobacilli; illness characterized by fluctuating fever; contact with contaminated dairy products/animal parts Brucella (brucellosis)
small, aerobic, nonmotile coccobacillus; pertussis, adhesins & toxins mdeiate disease; bacteria inhaled in aerosols/multiply in epithelial cells Bordetella
ubiquitous in soil/decaying matter, opportunistic pathogens Pseudomonads
only an opportunistic pathogen, can colonize any organ/system, difficult b/c of drug resistance Pseudomonas aeruginosa
universal inhabitants of water, intracellular parasites, elimination of bacteria not feasible (Pseudomonads) Legionella
normal microbiota of intestinal/upper respiratory tracts; abdominal infections, genital infections, wound infections of skin Bacteroides
Created by: bsulankey