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Unit 5 ACEIs & ARBs

LCC NURS 200 unit 5 ACEI's and ARBs

ACE Inhibitors – Prototype captopril (Capoten)
ACE Inhibitors MOA Prevent production of Angiotension II by blocking ACE
ACE Inhibitors Indications Hypertension, Heart failure, Renal protective effects in patients with diabetes, After MI
ACE Inhibitors Adverse Effects Relatively well tolerated. Fatigue/dizziness, hyperkalemia, dry nonproductive cough.
ACE Inhibitors Nursing Implication First does hypotensive effect may occurs. Monitor blood pressure, fall risk. Administer on an empty stomach.
ACE Inhibitors Contraindications/Cautions Allergies, hyperkalemia, hypotension, Renal insufficiency, Causes birth defects in 2nd and 3rd trimester.
ACE Inhibitors Interactions Caution with Potassium sparing diuretic, NSAIDS antagonize ACE Inhibitors, Monitor closely with other antihypertensives.
Angiotension II Receptor Blockers (ARBs) Prototype losartan (Cozaar, Hyzaar)
ARBs MOA Block the effect of AII by blocking receptors that receive AII.
ARB Adverse Effects Dizziness, GI distress (but can give with food), Headache. Does not cause dry cough, hyperkalemia less likely to occur.
ARB Contraindications/Cautions hypotension, renal insufficiency.
ARB Interactions. Careful with other antihypertensives
Created by: npeters519