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BIO 273
Stack #6264
| BIO 273 microbiology | BIO 273 Microbiology Ch. 16-17 |
|---|---|
| antigen | a molecule that reacts specifically with an antibody or immune lymphocyte |
| Immunoglobins | glycoproteins, recognize and bind to foreign substances increase phagocytosis, nueutralizes toxins |
| IgM | has five constant regions |
| epitope | part fo the antigen that is bound by the antibody |
| IgE | involved with allerigic reaction |
| T helper cells | kill virus infected cells |
| MHC class I proteins | present viral antigens when a cell is infected |
| MHC class II proteins | are present on only immune system cells |
| MHC class II proteins | present antigen to T helper cells |
| MHC class II proteins | are found on the professional antigen presenting cell |
| T cell dependant antigens | interact with plasma cells |
| clonal expansion | happens only with B cells that produce IgE |
| the cell-mediated immune response involves | MHC class I molecules, cytotoxic T cells, CD8 molecules, colonal expansion |
| cytoxic T cells | recognize virus infected cells, activated by tumor necrosis factor, kills target cells by inducing apoptosis, Contain CD8 |
| Opsonization | helps increas phagocytosis |
| CD4 + cells are | T helper cells |
| A plasma cell | a B cell that produces antibodies |
| Passive immunity | occurs naturally from mother to fetus |
| Passive artificial immunity | transfer of preformed antibodies |
| Active natural immunity | occurs in response to infections or other exposures |
| Active artificial immunity | occurs in response to vaccine administration |
| vaccine | a preparation of living or inactivated microorganisms or viruses or their components to induce active immunity |
| Attenuated immunixing agents | antigenic and can repicate, but are modified to be incapable fo causing disease under normal circumstances |
| Inactivated vaccines | contain inactivated whole agents or subunits of the agent |
| Recombinant vaccine | genetically engineered |
| adjuvants | increase the intensity of the immune response to the antigen in a vaccine |
| adaptive immunity | acquired throughout life |
| Humoral immunity | mediated by B-lymphocytes |
| activated in response to extracellular antigens | B-lymphocytes |
| B-lympocytes | proliferate and differentiate into plasma cells that produce antibodies |
| Cellular immunity | mediated by T-lymphocytes |
| T-cytoxic cells | destroy host cells that harbor intracellular agents such as viruses by inducing apoptosis |
| T-helper cells | potential cellular and humoral response |
| cell mediated immune response | involves T cells and their interactions with B cells |
| Humoral Immune response | involve B cells and their products, the immunoglobulins or antibodies |
| antigens | substances recognized as foreign by the components fo the immune response |
| somatic Ags | "O"; of the body or endotoxin layer |
| Capsular Ags | found in species with capsules |
| Flagellar Ags | "H"; in motile species |
| Exotoxins | toxins secreted by microorganisms into their external enviroment |
| E. Coli O157:H7 | Somatic Ags |
| Steptococcus pneumoniae | Capsular Ags |
| E. Coli O157:H7 | flagellar Ags |
| tetanus toxin | Exotoxin |
| hapten | a molecule too small to cause an immune response |
| hapten carrier complex | a hapten attached to a carrier molecule that makes it large enough to be recognized |
| IgG | monomer |
| IgM | pentamer |
| IgA found in bloodstream | monomer |
| IgA found in mucos membranes(secretory IgA) | Dimer |
| IgE | membrane receptor molecule, active immunity to helminth disease, immediate hypersenstivity disease.responds to allergies and parasites |
| causes the body to expel pathogens, through coughing sneezing, mucous production | IgE |
| protects baby until immune system develops, passes from mother to fetus | IgG |
| B cells | mature in bone marrow |
| T cells | mature in thymus |
| cell mediated immunity cells | T cells |
| antibody-synthesizing cells | B cells |
| Plasma cells | arise form B cells, to produce large amounts of antibodies |
| found on all human cells except RBC | Class I MHC |
| found principally on cacrophages and dendritic cells and are used by these cells to present antigen to the T cells | Class II MHC |
| T-helper cells | carry the CD4 receptor and control immunoresponse |
| T-cytotoxic cells | Carry the CD8 receptore and kill infected and cancerous cells |
| T-Suppressor cells | carry the CD8 receptor and suppress the immune system, to avoid autoimmune reactions |
| T-Delayed -type Hypersensitivity | carry the CD4 receptor and are involved in DTH |
| allow the body to recognize self versus non self cells | MHC molecules |
| Firtst antibody seen in a primary response to a particular antigen | IgM |
Created by:
netangel29
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