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RR Classic Pres D1

Classic Presentations Day 1

QuestionAnswer
abdominal pain, ascites, hepatomegaly budd-chiari syndrome
achilles tendon xanthoma familial hypercholesterolemia
adrenal hemorrhage, hypotension, DIC waterhouse-friedrichsen syndrome (meningococcemia)
arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints Marfan's syndrome (fibrillin defect)
Athlete with polycythemia Erythropoietin injection
Back pain, fever, night sweats, weight loss pott's disease (vertebral tb)
bilateral hilar adenopathy, uveitis sarcoidosis (non-caseating granulomas)
blue sclera osteogenesis imperfecta (type 1 collagen defect)
bluish line on gingiva burton's line (lead poisoning)
bone pain, bone enlargement, arthritis paget's disease of bone
bounding pulses, diastolic heart murmur, head bobbing aortic regurgitation
cafe-au-lait spots, lisch nodules (iris hamartoma) Neurofibromatosis type I (+ pheo, optic gliomas) Neurofibromatosis type II (+ bilateral acoustic neuromas)
cafe-au-lait spots, polyostotic fibrous dysplasia, precocious puberty McCune-Albright syndrome
calf pseudohypertrophy muscular dystrophy (MC-ly duchenne's)
cherry red spot on macula tay-sachs, niemann-pick (cherry picking disease!), central retinal a occlusion
chest pain, pericardial effusion/frction rub, persistent fever following MI dressler's syndrome (autoimmune mediated; 1-12 weeks post-acute MI)
child uses arms to stand up from squat gower's sign (duchenne)
child with fever develops red rash on face that spreads to body slapped cheeks; erythema infectiosum/fifth disease; parvovirus b19
chorea, dementia, caudate degeneration huntington's disease (CAG repeats)
chronic exercise intolerance with myalgia, fatigue, and painful cramps mcardle's disease (msucle phosphorylase deficiency)
cold intolerance hypothyroidism
conjugate lateral gaze palsy, horizontal diplopia internuclear ophthalmoplegia (damage to MLF; bilateral [MS], unilateral [stroke])
continuous machinery heart murmur pda (close with indomethacin, keep open with misoprostol=prostaglandin)
cutaneous/dermal edema due to CT deposition myxedema (hypothyroidism, Graves [pretibial myxedema])
dark purple skin/mouth nodules kaposi's sarcoma
deep, labored breathing/hyperventilation kussmaul's breathing (diabetic ketoacidosis; compensatory mechanism to correct acidosis of DKA)
dermatitis, dementia, diarrhea pellagra (niacin/b3 deficiency)
dilated cardiomyopathy, edema, polyneuropathy wet beri beri (thiamine/b1 deficiency)
dog or cat bite resulting in infection pasturella multocida (cellulitis at inoculation site)
dry eyes, dry mouth, arthritis sjogren's syndrome (autoimmune destruction of exocrine glands)
dysphagia (esophageal webs), glossitis, iron deficiency anemia plummer vinson syndrome (may progress to esophageal SCC)
elastic skin, hypermobility of joints ehler's danlos syndrome (type III collagen defect)
enlarged, hard, L suprclavicular node virchow's node (gi malignancy metastasis)
erythroderma (red skin), lymphadenopathy, hepatosplenomegaly, atypical T cells sezary dyndrome (cutaneous t cell lymphoma) or mycosis fungoides
facial m spasm upon tapping chvostek's sign (hypocalcemia)
fat, female, forty, and fertile acute cholelithiasis (bile duct blockage)
fever, chills, headache, myalgia following antibiotic treatment for syphilis Jarisch-Herxheimer reaction (rapid lysis of spirochetes results in toxin release)
fever, cough, conjunctivitis, coryza, diffuse rash measles (morbillivirus)
fever, night sweats, weight loss b symptoms (lymphoma) and TB
fibrous plaques in soft tissue of penis peyronie's disease (CT disorder)
gout, metnal retardation, self-mutilating behavior in a boy lesch-nyhan syndrome (hgprt deficiency, x linked recessive)
green-yellow rings around peripheral cornea kayser-fleischer rings (copper accumulation from wilson's disease)
hamartomatous gi polyps, hyperpigmentation of mouth/feet/hands peutz-jeghers syndrome (genetic benign polyposis can cause bowel obstruction; increased cancer risk)
hepatosplenomegaly, osteoporosis, neuro symptoms gaugher's disease (glucocerebrosidase deficiency; wrinkled tissue paper cytoplasm)
hereditary nephritis, sensorineural hearing loss, cataracts alport's syndrome (type IV collagen mutation); can't see, can't pee, can't hear
hypercoagulability (leading to migrating dvts and vasculitis) trousseau's sign (adenocarcinoma of pancreas or lung)
hyperphagia, hypersexuality, hyperorality, hyperdocility Kluver-Bucy syndrome (bilateral amygdala lesion); think of Gary Busey
hypertension, hypokalemia, metabolic acidosis conn's syndrome (primary hyperaldosteronism)
hypoxemia, polycythemia, hypercapnia blue bloater (chronic bronchitis: hyperplasia of mucus cells)
indurated, non-painful ulcerated genital lesion chancre (primary syphilis; treponema pallidum)
indurated, painful ulcerated genital lesion with exudate chancroid (haemophilus ducreyi)
Created by: sarah3148